摘要
目的探讨前列腺癌患者穿刺活检引发感染性休克的原因和护理措施，为减少前列腺活检感染性休克提供参考依据。方法回顾性分析84例行穿刺活检术的前列腺癌患者的一般资料，采用Logistic多因素分析的方法分析感染性休克的危险因素。结果84例患者中，有7例患者出现感染性休克，发生率为8．33％；7例感染性休克共检出致病菌10株，其中革兰阴性菌8株，革兰阳性菌2株。单因素分析结果显示，两组患者在年龄、合并糖尿病、合并前列腺感染、合并尿路感染、APACHE1I评分、反复穿刺方面比较差异有统计学意义（P〈0．05）；多因素Logistic回归分析结果显示，合并前列腺感染、年龄、合并尿路感染、APACHEII评分是前列腺癌患者行穿刺活检术引发感染性休克的主要危险因素（OR值分别为0．376，0．141，0．281，0．269；P〈0．05）。结论前列腺癌患者穿刺活检引发感染性休克的致病菌主要是以革兰阴性菌为主，发生时间多集中在术后48h内，对于APACHEII评分较低、年龄较大、合并前列腺感染或者尿路感染的患者要采取多角度的防控措施，以减少感染性休克的发生。
Objective To explore the causes and nursing measures of septic shock caused by biopsy in patients with prostate cancer, and to provide reference for reducing infectious shock. Methods The general data of 84 prostate cancer patients, who taken puncture biopsy, were retrospectively analyzed, and the causes of Septic shock were analyzed by the Pearson univariate analysis method and multivariate logistic regression analysis method. Results All 7 patients of septic shock were detected, with the occurrence rate 8.33%. A total of 10 strains of pathogenic bacteria were detected from those 7 patients, including 8 strains of gram negative bacteria and 2 strains of gram positive bacteria. There were significant difference between two groups on the age, diabetes complication, prostate infection complication, urinary tract infection complication, APACHE II score, repeated puncture （P 〈 0. 05 ）. Multivariate I^gistic regression analysis showed that prostate infection complication, age, urinary tract infection complication, APACHEllscore were major risks for septic shock induced by biopsy in prostate cancer patients （ OR =0. 376,0. 141,0. 281,0. 269, P 〈 0. 05）. Conclusions Septic shock is mainly caused by gram negative bacteria when biopsy is taken on prostate cancer patients and it mainly happens in 48 hours after the operation. Patients with lower APACHE II score, elder age, with prostate infections or with urinary tract infection should be given multi-angle prevention and treatment to reduce the incidence of septic shock.
出处
《中华现代护理杂志》
2015年第11期1276-1278,共3页
Chinese Journal of Modern Nursing
