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奥拉西坦联用B族维生素治疗血管性痴呆的疗效分析 被引量:5

Clinical effects of oxiracetam B-vitamins on vascular dementia
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摘要 目的:分析奥拉西坦联用不同药物治疗血管性痴呆的疗效差异。方法:63例血管性痴呆患者分为两组:单用奥拉西坦组、奥拉西坦联用维生素B12、维生素B6和叶酸组。对患者用药前后的MMSE评分和ADL评分进行比较,分析两组疗效差异。结果:两种治疗方式均可提高患者MMSE评分和ADL评分;奥拉西坦联用维生素B12、B6及叶酸组效果优于单用奥拉西坦组。结论:奥拉西坦联用族维生素B12、B6及叶酸能更好改善血管性痴呆的认知水平。 Objective: To observe the clinical effects of combined oxiracetam with B-vitamins and folic acid on vascular dementia. Methods: Sixty-three patients with vascular dementia were divided into two groups. Group I received oxiracetam,and GroupⅡ were given oxiracetam plus vitamin B12,B6 and folic acid. The two groups of patients were evaluated with Mini-Mental State Exam( MMSE) and Activities of Daily Living( ADL) before and after medication,and examined concerning the therapeutic effects. Results: Although two regimens had boosted the scores on MMSE and ADL,yet oxiracetam plus vitamin B12,B6 and folic acid had produced better results. Conclusion: Oxiracetam plus vitamin B12,B6 and folic acid may effective improve the recognition of patients with vascular dementia.
出处 《皖南医学院学报》 CAS 2015年第3期249-251,共3页 Journal of Wannan Medical College
关键词 血管性痴呆 同型半胱氨酸 奥拉西坦 B族维生素 vascular dementia homocysteine oxiracetam B-vitamins
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