期刊文献+

乌灵胶囊对缺血性脑卒中患者抑郁情绪及认知功能的影响

Effect of Wuling Capsule on Depression and Cognition Function of Patients with Ischemic Stroke
原文传递
导出
摘要 目的:探讨乌灵胶囊对缺血性脑卒中患者抑郁情绪和认知功能的影响。方法:将78例脑卒中患者随机分为治疗组(39例)和对照组(39例),均给予抗血小板凝聚、他汀类药物、神经营养药物、康复治疗等常规治疗,治疗组则在此基础上配合服用乌灵胶囊,观察两组患者事件相关电位(ERP)和HAMD评分的改善情况。结果:治疗8周后,两组患者N2PL、P3PL均显著缩短(P〈0.05),P3amp均显著升高(P〈0.05),HAMD评分均显著降低(P〈0.05),且治疗组均优于对照组(P〈0.01)。结论:乌灵胶囊能有效改善缺血性脑卒中患者的抑郁情绪和认知功能,对促进其预后和康复有一定临床价值。 Objective:To study the effect of Wuling capsule on depression and cognitive function of patients with ischemic stroke. Methods:78 pa-tients with stroke were randomly divided into treatment group (39 cases) and control group (39 cases), both with conventional treatment of anti-plate-let aggregation, statins, nerve nutrition medicine, rehabilitation and the like, treatment group added Wuling capsule, improvement in event related po-tentials (ERP) and HAMD scores of two groups were observed. Results:After treatment of 8 weeks, N2PL and P3PL of two groups were significant-ly shortened (P〈0.05), P3amp significantly increased (P〈0.05), HAMD score significantly decreased (P〈0.05), and treatment group was better than control group (P〈0.01). Conclusion:Wuling capsule can effectively improve the depression and cognitive function of patients with ischemic stroke, and has certain clinical value to promote its prognosis and rehabilitation.
出处 《按摩与康复医学》 2015年第9期18-20,共3页 Chinese Manipulation and Rehabilitation Medicine
基金 国家中医药管理局中医药重点学科-中医全科基金项目,编号:2013QK10
关键词 缺血性脑卒中 乌灵胶囊 抑郁情绪 认知功能 事件相关电位 ischemic stroke Wuling capsule depression cognitive function event related potential ,
  • 相关文献

参考文献13

  • 1Toso V, Gandolfo C, Palucci S, et al. Post-stroke depression re- search methodology of a large multicentre observational study [J]. Nettrol Sci,2004,25(2): 138-144.
  • 2李亚明,潘永福.乌灵胶囊治疗老年失眠症[J].中国新药与临床杂志,2006,25(4):289-291. 被引量:11
  • 3高力舒,谢健.乌灵胶囊和帕罗西汀治疗广泛性焦虑的疗效观察[J].中国实用神经疾病杂志,2007,10(2):124-125. 被引量:14
  • 4各类脑血管疾病诊断要点[J].中华神经科杂志,1996,29(6):379-380. 被引量:33029
  • 5刘晶,韩杰,赵红玲,高淑敏,张庆元,许晶.首发急性单一病灶脑卒中患者抑郁程度与认知功能的关系[J].中国临床康复,2004,8(7):1204-1205. 被引量:14
  • 6Sato S, Yamakawa Y, Terashima Y, et al. Efficacy of milnacipran on cognitive dysfunctionwith Post-stroke depression: Preliminary open label study[J]. Psychiatry Clin Neurosci,2006,60(5):584-589.
  • 7Joubert J, Reid C, Joubert L, et al. Risk factor management and depression Post-stroke: the value of an integrated model of care [J]. J Clin Neurosci,2006,13(1):84-90.
  • 8Morris PL, Bear H, Fries S, et al. Association of depression with 10-year post-stroke mortality[J]. Am J Psyehiatry,1993,150(1): 124-129.
  • 9Cross JJ. The emerging field of emotion regulation: An integrativereview[J]. Review of general Psyeholosy,1998,2(3):271-299.
  • 10Narushima K, Chan KL, Kosier JT, et al. Does cognitive recovery after treatment of poststroke depression last? A 2-year follow-up of cognitive function associated with poststroke depression[J]. Am J Psychiatry,2003,160(6): 1157-1162.

二级参考文献32

  • 1张顺泉,张海生,谢健.广泛性焦虑障碍的临床治疗[J].中国心理卫生杂志,2004,18(6):436-436. 被引量:4
  • 2脑卒中患者临床神经功能缺损程度评分标准(1995)[J].中华神经科杂志,1996,29(6):381-383. 被引量:15752
  • 3四川省中医中药研究所.四川中药志,第2册[M].成都:四川人民出版社,1960.1434.
  • 4徐叔云.中药临床药理[M].北京:华夏出版社,1997.1217-1218.
  • 5徐叔云,中药临床药理,1997年,1217页
  • 6徐叔云,药理实验方法学(第2版),1991年,657页
  • 7夏宗勤,实验核医学与核药学,1989年,255页
  • 8四川省中医中药研究所,四川中药志.2,1960年,1434页
  • 9Robinson RG,Bolla-Wilson K,Kaplan E,et al.Depression influences intellectual impairment in stroke patients.Br J Psychiatry 1986;148:541-7
  • 10Caine ED.Pseudo-dementia.Arch Gen Psychiatry 1981; 38:1359-64

共引文献33218

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部