摘要
目的探讨氟伏沙明联合利培酮治疗强迫症疗效。方法 2012年7月-2013年7月收治强迫症患者25例,给予氟伏沙明联合利培酮治疗,设为观察组;并以同期单纯给予利培酮治疗的25例患者为对照组,于治疗前以及治疗4、8周后,使用Y-BOCS（耶鲁-布朗强迫症状量表）及TESS（副反应量表）评定疗效及不良反应。结果观察组治疗后Y-BOCS评分明显高于治疗前,对比差异具有统计学意义（P〈0.05）;治疗后观察组Y-BOCS评分明显高于对照组,组间比较差异具有统计学意义（P〈0.05）;两组治疗后TESS评分差异无统计学意义（P〉0.05）。结论临床治疗强迫症使用氟伏沙明联合利培酮治疗的方式,效果突出,相比单纯的利培酮治疗,效果更加优秀,临床中具有很高应用价值。
Objective To investigate the curative effect of fluvoxanfine combined with risperidone in the treatment of obsessive-compulsive disorder. Methods July 2012 - 2013 July treated patients with obsessive-compulsive disorder （OCD）25 cases, giving fluvoxamine combined with risperidone in the treatment, as the observation group; and at the same time treated with risperidone in the treatment of 25 patients as control group, before treatment and treatment 4 and 8 weeks after using Y-BOCS （ Yale - Brown strong forced symptom table ） and Tess （ adverse reactions were table ） to assess the efficacy and adverse reaction. Results After treatment, the observation group the Y-BOCS score was sigalificantly higher than the treatment before, the difference has statistical significance （ P〈 0.05 ） . After treatment, the observation group Y-BOCS score was significantly higher than that of the control group, the diffirence between the two groups has statistical significance （ P〈 0.05 ） ; after treatment in the two groups of Tess score difference no statistical significance （ P〉0.05 ） . Conclusion Using the fluvoxamine combined with risperidone in the treatment in the clinical treatnaent of obsessivecompulsive disorder （ OCD ）, and the effect is outstanding, compared to risperidone treatment alone, the effect is more outstanding, the clinic has a high application value.
出处
《中国卫生标准管理》
2015年第12期75-76,共2页
China Health Standard Management
关键词
氟伏沙明
利培酮
强迫症
治疗
Fluvoxamine, Risperidone, Obsessive-compulsive disorder, Therapy
