摘要
目的:探讨手术联合自拟清热燥湿方熏洗治疗陈旧性肛裂临床效果及安全性。方法:选取医院肛肠科2010年5月—2014年5月收治陈旧性肛裂患者140例,采用随机数字表法分为对照组和试验组,每组各70例;两组患者均行部分内括约肌切除手术治疗,其中对照组患者术后采用高锰酸钾熏洗坐浴治疗;试验组患者则术后采用自拟清热燥湿方熏洗坐浴治疗;比较两组患者临床疗效,创面愈合时间,治疗前后肛门静息压、生存质量测定量表简表评分及并发症发生情况等。结果:试验组患者临床疗效显著优于对照组,差异有统计学意义(P<0.05);试验组患者创面愈合时间显著短于对照组,差异有统计学意义(P<0.05);两组患者治疗后肛门静息压和生存质量测定量表简表评分较治疗前显著改善,且试验组患者治疗后两项指标水平优于对照组,差异有统计学意义(P<0.05);试验组患者并发症发生率显著低于对照组,差异有统计学意义(P<0.05)。结论:手术联合自拟清热燥湿方熏洗治疗陈旧性肛裂可有效缓解临床症状体征,降低肛门静息压,改善生存质量,并有助于提高治疗安全性。
Objective ： To investigate clinical effects and safety of surgery combined with self - made Qingrezashi decoc- tion on chronic anal fissure fumigation. Methods ： 140 patients with chronic anal fissure fumigation in Anorectal Department were chosen in the period from May 2013 to May 2014 in our hospital and randomly divided into both groups including control group （70 patients） with fumigation and washing recipe by Potassium Permanganate treatment and experiment group （70 patients） with fumigation and washing recipe by self - made Qingrezashi decoction treatment after surgery; and the clinical efficacy, wound healing time, anal resting pressure and QOL - BREF score before and after treatment and com- plications occurrence of both groups were compared. Results：The clinical efficacy of experiment group was significantly better than that of control group（P 〈0.05）. The wound healing time of experiment groups was significantly shorter than that of control group（ P 〈： 0.05 ）. The anal resting pressure and QOL - BREF score after treatment of both group was sig- nificantly better than before treatment（ P 〈 0.05 ）. The anal resting pressure and QOL - BREF score after treatment of ex- periment group was significantly better than that of control（ P 〈 0.05 ）. The complication incidence of experiment group was significantly lower than that of control group（ P 〈 0. 05 ）. Conclusion：Surgery combined with self- made Qingrezashi decoction on chronic anal fissure fumigation can efficiently relieve clinical symptoms and signs, reduce anal resting pres- sure, improve quality of life and be helpful to higher the treatment security.
出处
《中华中医药学刊》
CAS
北大核心
2015年第6期1509-1511,共3页
Chinese Archives of Traditional Chinese Medicine
关键词
手术
中药
陈旧性肛裂
疗效
安全性
surgery
TCM
chronic anal fissure fumigation
clinical efficacy
safety
