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老年晚期非小细胞肺癌治疗进展 被引量:32

Advances in the management of elderly patients with advanced nonsmall cell lung cancer
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摘要 肺癌是一种老年性疾病,目前针对老年非小细胞肺癌患者的治疗正面临着极大的挑战。尽管有50%以上的非小细胞肺癌患者在诊断时的年龄已超过70岁,但针对这类患者的研究却十分有限。许多晚期老年患者未获得最佳治疗或已失去了最佳治疗的机会。本文旨在通过整理和分析现有的相关研究,总结老年晚期非小细胞肺癌患者最适宜的治疗方案。 Lung cancer is a disease of the elderly. Nowadays, the management of elderly patients with non-small cell lung cancer(NSCLC) is challenging. Despite the fact that more than 50% of patients with NSCLC are elderly( 70 years old), information remains scant on these patients. Many older patients with advanced NSCLC do not receive or have lost the chance of optimal management. The goal of this review is to sort and analyze the information obtained from published literatures and to provide guidance on how to treat elderly patients with advanced NSCLC more appropriately.
出处 《肿瘤》 CAS CSCD 北大核心 2015年第5期579-583,共5页 Tumor
基金 上海市级医院适宜技术项目(老年晚期非小细胞肺癌规范个体化治疗的推广)(编号:SHDC12012208)~~
关键词 非小细胞肺 老年人 管理 Carcinoma non-small cell lung Elderly Management
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  • 1Siegel R, Ma J, Zou Z, et al. Cancer statistics, 2014[J]. CA Cancer J C/in, 2014, 64(1):9-29.
  • 2Owonikoko TK, Ragin CC, Belani CP, et al. Lung cancer in elderly patients: An analysis of the Surveillance, Epidemiology, and End Results database[J]. J Clin Oncol, 2007, 25(35):5570-5577.
  • 3Wingo PA, Cardinez CJ, Landis SH, et al. Long-term trends in cancer mortality in the United States, 1930-1998[J]. Cancer, 2003, 97(12):3133-3275.
  • 4Davidoff AJ, Tang M, Seal B, et al. Chemotherapy and survival benefit in elderly patients with advanced non- small cell lung cancer[J].J Clin Onto/, 2010, 28(13):2191-2197.
  • 5Davidoff AJ, Gardner .IF, Seal B, et a/. Population-based estimates of survival benefit associated with combined modality therapy in elderly patients with locally advanced non-small cell lung cancer[J].J Thorac Oncol, 2011,6(5):934-941.
  • 6Hutchins LF, Unger JM, Crowley JJ, et al. Underrepresentation of patients 65 years of age or older in cancer- treatment trials[J]. N EnglJ Med, 1999, 341 (27):2061-2067.
  • 7Effects of vinorelbine on quality of life and survival of elderly patients with advanced non-small-cell lung cancer. The Elderly Lung Cancer Vinorelbine italian Study Group[J]. J Natl Cancer Inst, 1999, 91(1):66-72.
  • 8Ansari RH, Socinski MA, Edelman MJ, et al. A retrospective analysis of outcomes by age in a three-arm phase m trial of gemcitabine in combination with carboplatin or paclitaxel vs. paclitaxel plus carboplati'n for advanced non-small cell lung cancer[J]. Crit Rev Oncol Hematol, 2011,78(2):1 62-1 71.
  • 9Gridelli C, Perrone F, Gallo C, et al. Chemotherapy for elderly patients with advanced non-small-cell lung cancer: The Multicenter Italian Lung Cancer in the Elderly Study (MILES) phase III randomized trial[J]. J Nat/ Cancerlnst, 2003, 95(5):362-372.
  • 10Quoix E, Zalcman G, Oster JP, et al. Carboplatin and weekly paclitaxel doublet chemotherapy compared with monotherapy in elderly patients with advanced non-small-cell lung cancer: IFCT-0501 randomised, phase 3 trial[J]. Lancet, 2011, 378(9796):1079-1088.

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