摘要
目的 探讨心力衰竭（HF）患者促甲状腺激素（TSH）水平与心力衰竭预后的关系.方法 回顾性分析2010年1月至2013年12月在我院住院诊断为急性心力衰竭的48例患者,其心功能按照美国纽约心脏病协会（NYHA）标准分级均为Ⅳ级,测定患者血清中游离甲状腺原氨酸（FT3）、游离甲状腺素（FT4）、促甲状腺素（TSH）水平.根据TSH水平分为两组：TSH水平下降者纳入A组,TSH水平正常者纳入B组.采用x2检验判断两组患者TSH水平组间差异性,以及两组患者住院期间死亡率、90 d病死率间是否存在统计学差异.结果 两组患者入院时基础资料及心功能分级未见统计学差异（P＞0.05）;A、B两组患者TSH水平分别为（1.12±0.55）mIU/L和（2.98±0.53）mIU/L,差异具有统计学意义（P＜0.05）;A、B两组患者住院期间死亡率分别为41.67％和0％,90 d病死率分别为58.33％和8.33％,A、B两组相比差异具有统计学意义（P＜0.05）.结论 TSH水平可以作为心力衰竭患者预后的预测指标.
Objective To investigate the level of thyroid stimulating hormone（TSH） in patients with heart failure（HF）, determine the relationship between TSH and mortality in patients with HF. Methods A retrospective analysis of 48 patients with acute heart failure admitted to our hospital from January 2010 to December 2013. Car- diac function are all grade IV according to the New York Heart Association （NYHA） cardiac functional standard. The serum levels of free triiodothyronine（FT3 ）, free thyroxin（FT4）, thyroid-stimulating hormone（TSH ） were mea- sured in patients. The patients were divided two groups according to the level of TSH, decreased TSH are in group A, normal TSH in group B. Results The TSH level of two groups were respectively（1.12± 0.55）mlU/L, （2.98± 0.53 ）mlU/L, there was a difference （P〈0.05）; the in-hospital mortality rates of two groups were respectively 41.67%, 0%, 90 d case fatality rates were respectively 58.33%, 8.33%, there was a difference compared with A and B two groups （P〈0.05）. Conclusion The levels of the TSH can be used as the indicators to evaluate the nro^nosis of HF.
出处
《中国心血管病研究》
CAS
2015年第5期417-419,共3页
Chinese Journal of Cardiovascular Research
关键词
心力衰竭
促甲状腺激素
死亡率
预后
Heart failure
Thyroid stimulating hormones
Mortality
Prognosis
