期刊文献+

肝动脉化疗栓塞与伽玛刀序贯联合疗法在中晚期肝细胞癌治疗中的临床应用 被引量:2

下载PDF
导出
摘要 目的对肝动脉化疗栓塞与伽玛刀序贯联合疗法在中晚期肝细胞癌患者治疗中的临床应用价值进行探讨。方法 74例中晚期肝细胞癌患者,随机分为观察组(38例)和对照组(36例),对照组患者仅采取肝动脉化疗栓塞治疗,观察组患者采取肝动脉化疗栓塞与伽玛刀序贯联合疗法治疗。观察并比较两组的临床疗效。结果观察组患者的甲胎蛋白水平降低例数明显多于对照组,差异具有统计学意义(P<0.05);观察组患者的总有效率显著高于对照组,差异具有统计学意义(P<0.05);观察组患者的生存率高于对照组,差异具有统计学意义(P<0.05)。结论治疗中晚期肝细胞癌患者采取肝动脉化疗栓塞与伽玛刀序贯联合疗法,能够明显提高患者预后质量,增强治疗效果,延长生存期限。
作者 雒润华
出处 《中国实用医药》 2015年第14期96-97,共2页 China Practical Medicine
  • 相关文献

参考文献3

二级参考文献22

共引文献23

同被引文献36

  • 1Luo J,Peng ZW,Guo RP,et al.Hepatic resection versus transarterial lipiodol chemoembolization as the initial treatment for large,multiple,and resectable hepatocellular carcinomas:a prospective nonrandomized analysis[J].Radiology,2011,259(1):286-295.
  • 2Nielsen DL,Palshof JA,Larsen FO,et al.A systematic review of salvage therapy to patients with metastatic colorectal cancer previously treated with fluorouracil,oxaliplatin and irinotecan+/-targeted therapy[J].Cancer Treat Rev,2014,40(6):701-715.
  • 3Kudo M,Imanaka K,Chida N,et al.Phase III study of sorafenib after transarterial chemoembolisation in Japanese and Korean patients with unresectable hepatocellular carcinoma[J].Eur J Cancer,2011,47(14):2117-2127.
  • 4Matsuda M,Omata F,Fuwa S,et al.Prognosis of patients with hepatocellular carcinoma treated solely with transcatheter arterial chemoembolization:risk factors for oneyear recurrence and two-year mortality(preliminary data)[J].Intern Med,2013,52(8):847-853.
  • 5Zheng J,Shao G,Luo J.Analysis of survival factors in patients with intermediate-advanced hepatocellular carcinoma treated with transcatheter arterial chemoembolization combined with sorafenib[J].Clin Transl Oncol,2014,16(11):1012-1017.
  • 6Shim JH,Park JW,Kim JH,et al.Association between increment of serum VEGF level and prognosis after transcatheter arterial chemoembolization in hepatocellular carcinoma patients[J].Cancer Sci,2008,99(10):2037-2044.
  • 7Park JW,Koh YH,Kim HB,et al.Phase II study of concurrent transarterial chemoembolization and sorafenib in patients with unresectable hepatocellular carcinoma[J].J Hepatol,2012,56(6):1336-1342.
  • 8Drake RR,Schwegler EE,Malik G,et al.Lectin capture strategies combined with mass spectrometry for the discovery of serum glycoprotein biomarkers[J].Mol Cell Proteomics,2006,5(10):1957-1967.
  • 9魏照光,陆骊工,邵培坚,胡宝山,李勇,张磊,何旭,禹娴怡,罗小宁.肝动脉化疗栓塞联合索拉非尼治疗中晚期肝细胞癌的临床疗效观察[J].中华放射学杂志,2012,46(3):252-256. 被引量:27
  • 10赵运胜,王猛,李军良,吴侠,李洪臣.血清高尔基体蛋白73、异常凝血酶原、磷脂酰基醇蛋白聚糖-3和甲胎蛋白联合检测对原发性肝癌的早期诊断价值研究[J].中国全科医学,2012,15(32):3730-3733. 被引量:24

引证文献2

二级引证文献1

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部