摘要
目的探讨ST段抬高型心肌梗死(SETMI)患者不同时间经桡动脉行冠状动脉介入术(PCI)的安全性和有效性。方法选取ST段抬高型心肌梗死患者连续病例100例并分为两类,即就诊时间12h内直接进行PCI的连续病例35例(A组)、溶栓后12h内进行PCI的连续病例65例(B组)。主要测定终点是PCI术后患者的心肌灌注水平,将患者在治疗期间的出血并发症发生率和规定时间内的心脏不良事件(MACE)发生情况作为次要终点事件。结果A组的IRA血栓积分偏低,而通过TIMI血流分级(TFG)和TIMI记帧(CTFC)测量的血流级别显示3级的比例高些(P<0.05)。A组和B组的CTFC数值有着很大的差别,A组大于B组[(27.32±4.95)vs(31.04±9.03),P<0.05],而TMPC的3级比例B组高于A组。肌酸激酶同工酶(CK-MB)峰值B组有下降趋势。出血并发症发生率、MACE发生率对于测定结果没有直接的影响。结论溶栓后早期经桡动脉行PCI治疗安全有效,值得临床重视。
Objective To investigate the safety and effectiveness of different time transradial percutaneous coronary intervention（PCI）in patients with ST segment elevation myocardial infarction（SETMI）.Methods One hundred patients with SETMI were divided into two groups：Group A（n =35）undergoing directly consecutive PCI within 12 h,and group B（n =65）undergoing PCI after thrombolysis within 12 h.The main endpoint was the determination of the level of myocardial perfusion in patients after PCI staff will major adverse cardiac events（MACE）incidence of bleeding complications in patients with officers during the time of treatment and the occurrence of specified as a secondary endpoint.Results The results could be seen from the results of group A low credit infarct-related artery（IRA）thrombus,and blood levels by thrombolysis in myocardial infarction（TIMI）flow grade（TFG）and corrected TIMI frame count（CTFC）levels measured 3 ratio higher（P〈0.05）.The CTFC values in group A were more than that in group B[（27.32±4.95）vs（31.04±9.03）,P0.05].The proportion of TMPG＇s three in group B was higher than that in group A.From CK-MB peak point of view in group B,there was a downward trend.The incidence of bleeding complications,MACE rates had no direct effect on the measurement results.Conclusion Early transradial PCI after thrombolysis is safe and effective.
出处
《中西医结合心脑血管病杂志》
2015年第5期612-614,共3页
Chinese Journal of Integrative Medicine on Cardio-Cerebrovascular Disease
关键词
ST段抬高型心肌梗死
经桡动脉行PCI
安全性
有效性
ST segment elevation myocardial infarction transradial percutaneous coronary intervention safety effectiveness
