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抗甲状腺药物治疗妊娠甲亢对新生儿甲状腺功能的影响 被引量:1

Impact of antithyroid drugs in treatment of gestational hyperthyroidism for neonatal thyroid function
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摘要 目的探讨分析抗甲状腺药物治疗妊娠甲亢对新生儿甲状腺功能的影响。方法回顾性分析2012年1月1日—2013年1月1日期间该院的60例妊娠甲亢患者的临床资料,根据治疗方式分为对照组(30例)和试验组(30例)。对照组患者被给予非抗甲状腺药物治疗,试验组患者被给予抗甲状腺药物治疗,观察、比较两组患者的治疗结果。结果对照组不良结局比(46.66%)高于试验组不良结局比(10.00%);P<0.05,差异具有统计学意义;试验组的TSH、FT3、FT4等甲状腺功能均优于对照组,P<0.05,差异具有统计学意义。结论抗甲状腺药物治疗妊娠甲亢后可显著提升新生儿甲状腺功能,减少可妊娠不良结局,应于临床中合理推广。 Objective To observe and analyze Impact of antithyroid drugs in treatment of gestational hyperthyroidism for neonatal thyroid function. Methods Retrospective analyzed clinical data in 60 cases of pregnancy in patients with hyperthyroidism between date of January 1, 2012 to January 1 2013 in our hospital, they were divided into control group (30 cases) and the experimental group (30 cases) according to the treatment. Patients in the control group were given a non-antithyroid drug treatment, the test group of patients were given anti-thyroid drug treatment, observation and comparin of treatment outcome between the two groups of patients. Results the control group of adverse outcomes(46.66%) was higher than outcomes in the experimental group (10.00%); P〈0.05, there was statistically significant; TSH of test group, FT3, FT4 and other thyroid function was better than the control group, P〈0.05,there was statistically significant. Conclusion after antithyroid drug therapy of gestational hyperthyroidism can significantly improve neonatal thyroid function, which can reduce adverse outcomes of pregnancy, it should be reasonable promotion in clinic.
出处 《中外医疗》 2015年第6期106-108,共3页 China & Foreign Medical Treatment
关键词 抗甲状腺药物 妊娠甲亢 新生儿甲状腺功能 影响 Antithyroid drugs gestational hyperthyroidism neonatal thyroid function the impact
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