摘要
目的探析脑淋巴瘤与胶质母细胞瘤的MRI动态增强特征及其对其鉴别诊断的价值。方法入选该院2012年5月-2014年4月经病理检查确诊为脑淋巴瘤26例及胶质母细胞瘤35例,进行MRI平扫及动态增强扫查,比较二者之间的MRI影像学特征。结果胶质母细胞瘤患者的MCER、EP、T_(max)与脑淋巴瘤患者比较,差异有统计学意义(P<0.05);10例脑淋巴瘤的MRI平扫结果未DWI弥散呈不均匀略高信号,而T2WI混杂长信号,T1WI混杂囊实性长信号;16例脑淋巴瘤占位效应及水肿相对较轻,而EWI呈均匀高信号,T2WI略长信号,T1WI略长或实性等长信号;而胶质母细胞瘤MRI扫查特征为DWI呈混杂性高信号,T1WI占位效应及水肿显著,T2WI混杂长信号,T1WI囊实性混杂长信号;二者MRI动态增强特征为:①强化形态:10例脑淋巴瘤呈环形不规则强化,18例脑淋巴瘤呈团块状显著强化,而胶质母细胞瘤病灶呈不均匀显著强化,为囊实性、结节状、花环样强化;②时间-信号强度曲线类型:脑淋巴瘤26例平台型17例,缓升型9例;胶质母细胞瘤35例中速升型6例,平台型16例,缓升型3例。结论脑淋巴瘤及胶质母细胞瘤进行MRI平扫及增强扫描对二者之间的鉴别诊断具有重要的临床价值。
Objective To study the characteristics of MRI dynamic enhancement and differential diagnosis value for glioblastoma and cerebral lymphoma.Methods Through pathological examination, 26 patients with cerebral lymphoma and 35 patients with glioblastoma treated from May 2012 to April 2014 in our hospital were selected. Through MRI plain scan and dynamic enhancement scan, their MRI imaging characteristics were compared.Results MCER, EP and Tmax for patients with glioblastoma compared with patients with cerebral lymphoma,difference was statistically significant （P〈0.05）; Based on MRI plain scan for 10 cases with cerebral lymphoma,DWI appeared the unevenly higher signals with T2WI mixed lasting signals and T1WI mixed cyst-solid lasting signals. For 16 patients with cerebral lymphoma, mass effects and edema were mild; EWI appeared the evenly high signals with T2WI lasting signals and T1WI lasting or solid isometric signals. Based on MRI scan for glioblastoma, DWI appeared the mixed high signals with significant T1WI mass effect and edema, T2WI mixed lasting signals and T1WI mixed cyst-solid lasting signals. Their dynamic enhancement characteristics： ① Enhancement： For 10 cases with cerebral lymphoma, the signals were enhanced in a irregular and ring way. For 18 cases with cerebral lymphoma, the signals were enhanced in a clustering way. For nidus of glioblastoma, the signals were enhanced in an uneven, cyst-solid, nodular and ring manner; ② TIC： For patients with cerebral lymphoma, 17 cases were evenly enhanced, 9 cases in a slow way. For patients with glioblastoma, 6 cases were rapidly raised, 16 cases in an even way and 3 cases in a slow way.ConclusionMRI plain and enhancement scan has the significant value of differential diagnosis for cerebral lymphoma and glioblastoma.
出处
《中外医疗》
2015年第11期178-179,共2页
China & Foreign Medical Treatment
