摘要
目的探讨干细胞移植应用于脑卒中的临床疗效。方法选择2012年6月至2013年6月南阳南石医院收治的脑卒中患者114例,依据随机数字表法将患者分为两组:对照组(58例)采用康复治疗,观察组(56例)采用干细胞移植疗法治疗,比较两组患者的疗效、神经功能缺损评分改变和日常生活能力(ADL)改变等情况。结果治疗后,观察组功能独立性测定评分显著高于对照组[(99.9±7.6)分比(97.2±7.4)分],Hachinski缺血量表评分显著低于对照组[(6.5±1.0)分比(6.9±1.0)分],ADL评分显著高于对照组[(62.9±16.8)分比(50.0±17.0)分],差异均有统计学意义(均P<0.01)。结论干细胞移植应用于脑卒中患者可有效改善独立功能,提高神经功能和日常生活活动能力。
Objective To explore clinical effect of stem cell transplantation on cerebral apoplexy . Methods A total of 114 patients with cerebral apoplexy admitted in Nanshi Hospital from Jun.2012 to Jun. 2013 were chosen as research objects and randomly divided into two groups.Patients in the observation group （58 cases） were given rehabilitation therapy,while patients in the control group（56 cases） were treated with stem cell transplantation.The curative effects,changes of neurological deficit scores,and activities of daily living（ADL） of the two groups were compared.Results After treatment,the functional independence meas-urement score of the observation group was significantly higher than that of control group [（99.9 ±7.6） vs （97.2 ±7.4）]; Hachinki ischemic score of the observation group was significantly lower than that of control group [（6.5 ±1.0） vs （6.9 ±1.0）];ADL score of the observation group was significantly higher than that of the control group [（62.9 ±16.8） vs （50.0 ±17.0）].All of the differences were statistically significant （P〈0.01）.Conclusion Stem cell transplantation can help patients with cerebral apoplexy to improve their independent function,neurological function,and activities of daily living effectively.
出处
《医学综述》
2015年第10期1875-1877,共3页
Medical Recapitulate
关键词
脑卒中
干细胞移植
临床疗效
Cerebral apoplexy
Stem cell transplantation
Clinical effect
