摘要
微循环功能障碍参与了糖尿病及其并发症的发病机制,其机制包括胰岛微循环功能异常影响胰岛β细胞的生理功能、微血管自律运动功能受损导致外周肌肉组织胰岛素抵抗、靶器官微循环功能障碍引起的靶细胞进行性损伤等。
Microcirculation dysfunction is involved in the onset of diabetes and its complications. The pathophysiological mechanisms behind the relationship between microcirculation and diabetes are multifactorial. Islet microcirculation dysfunction affects function of islet β cells. Impairment of microvascular vasomotion might be associated with insulin resistance. Microcirculation dysfunction of target organs mediates diabetic complications.
出处
《中华内分泌代谢杂志》
CAS
CSCD
北大核心
2015年第5期471-473,共3页
Chinese Journal of Endocrinology and Metabolism
关键词
糖尿病
微循环
发病机制
Diabetes mellitus
Microcirculation
Pathogenesis