摘要
目的 研究探讨HbF水平在β-地中海贫血携带者妊娠期产前筛查中的应用.方法 选取孕妇204例作为研究对象,检测其HbF水平和β-地中海贫血基因携带情况,并与300例未妊娠女性比较.结果 β-地中海贫血基因携带者HbF水平升高的比例、HbF升高水平均显著高于正常女性（P＜0.05）.妊娠女性HbF水平升高的比例显著高于未妊娠女性（P＜0.05）;携带β-地贫基因妊娠女性HbF水平升高的比例显著高于未妊娠女性（P＜0.05）.结论 HbF水平对于β-地中海贫血的产前筛查具有一定指导意义.
Objective To study HbF levels in the prenatal screening for beta thalassaemia carriers during pregnancy.Methods 204 pregnant women were selected as study objects.Their HbF levels and β-thalassemia genes were detected,and the results were compared with those of 300 non-pregnant women.Results More ones got an increase in HbF level and the HbF level increased much more in the β-thalassemia gene carriers than in the normal women （P〈0.05）.More ones got an increase in the pregnant than non-pregnant women （P〈0.05）.Conclusion HbF for prenatally screening beta thalassaemia has certain guiding significance.
出处
《国际医药卫生导报》
2015年第11期1557-1558,共2页
International Medicine and Health Guidance News
