摘要
目的:了解国内药物经济学评价研究的现状,为提高其研究水平和加强其规范性提供参考。方法:以中国期刊全文数据库、中文科技期刊数据库、万方数据资源系统为统计源,以"篇名/关键词/摘要"为检索项,从基本概况、研究设计、研究对象、研究角度、成本测算、评价方法及结果阐释等方面分析2009-2013年国内专业学术期刊上发表的1 127篇药物经济学评价文献。结果与结论:我国的药物经济学评价文献数量稳步增加,但大多数文献仍为成本-效果分析,存在的主要问题包括研究单位类型单一、未能明确表明作者利益冲突、样本代表性不强、对照方案的选择标准不明晰、成本测算不尽合理、结果表达不准确、不确定性分析缺失等。建议由多个部门及组织共同参与药物经济学评价指南的修订与发布,从各个层面对药物经济学研究进行规范和完善。
OBJECTIVE: To study the status of pharmacoeconomics evaluation in China, and provide references for improving its quality and strengthening its standardization. METHODS: A total of 1 127 pharmacoeconomics evaluation literatures published in academic journals in China from 2009 to 2013 were collected from CNKI, VIP and Wanfang database with the combination key- words of "name/keyword/abstract" and analyzed in terms of general situation, design, objects, perspective, measurement and calcu lation of costs evaluation method and results interpretation, etc. RESULTS & CONCLUSIONS: The number of pharmacoeconom ics evaluation literatures was increased in China. Most literatures were still applied methods of cost-effect analysis with the main problems of single research institutes types, unclear interest conflict of authors, no representative samples, ambiguous criterion of comparators types, unreasonable cost calculation, inaccurate explanation of outcomes and lack of uncertainty analysis, etc. It is suggested to revise and publish the pharmacoeconomics evaluation guideline by multiple departments and organizations to standardize and optimize pharmacoeconomics evaluation research from multi-levels.
出处
《中国药房》
CAS
北大核心
2015年第17期2305-2307,共3页
China Pharmacy
基金
国家自然科学基金资助项目(No.71463007)
贵州省科技计划课题(No.黔科合SY字[2013]3068号)
贵州省教育厅高校人文社会科学研究项目(No.黔教社发[2013]419号)
贵阳医学院院基金资助项目(No.院基金合同字第[2013]05号)
关键词
药物经济学
文献计量学
系统评估
文献
指南
Pharmacoeconomics
Bibliometrics
System assessment
Literature
Guideline