摘要
目的探讨五种不同职业对精子DNA完整性和精子参数的影响。方法将就诊的1658例男性不育患者按照职业分为司机组、放射科医生组、工人组,飞行员组和厨师组;将856例正常生育组做为健康对照组。采用SQA-V全自动精子分析仪进行精液常规分析,精子形态采用改良巴氏染色法,精子DNA完整性检测采用精子染色质扩散试验(SCD),用DNA断裂指数(DFI)表示。结果司机组、放射科医生组、工人组,飞行员组和厨师组的精子密度、活动率、精子形态和DFI与对照组比较差异有统计学意义(P<0.05);而精液量、精液p H值差异无统计学意义(P>0.05)。结论司机、放射科医生、工人,飞行员和厨师的职业可以影响精液质量,从而导致男性不育。
Objectives.. To explore the effect of five different occupations on male sperm DNA integrity and sperm parameters. Methods： 1658 cases of male infertility patients will be divided into drivers, radiation workers, pilots, chefs and workers of 5 teams, 856 contro 1 cases were recruited for the study; sperm parameters were analysised by fully automated SQA-V sperm analyzer; sperm morphology were analysised by modified papanicolaou staining method~ sperm DNA integrity was evaluated by sperm chromatin dispersion （SCD） , and the results were expressed interms of DNA fragmentation index （DFI） .Results： A significant difference in the concentration and mobility and sperm morphology and DFI of sperm between5 teams （P〈0.05） . But there is no difference in the semen volume and PH between them. （P〉0.05） . Conclusion： Occupations of drivers, radiation workers, pilots, chefs and workers affect routine semen parameters and sperm DNA integrity and result in m ale infertility.
出处
《中国优生与遗传杂志》
2015年第5期120-121,共2页
Chinese Journal of Birth Health & Heredity
关键词
职业
精子DNA完整性
精子参数
男性不育
Occupation
Sperm DNA integrity
Sperm parameters
Male infertility
