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先天性高胰岛素血症诊治进展 被引量：7

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摘要 先天性高胰岛素血症（congenital hyperinsulinism,CHI）是指由于各种先天病因导致胰岛素过量分泌而出现低血糖的病症,CHI是婴幼儿和儿童持续性复发性低血糖的重要原因之一,主要由胰岛β细胞异常分泌胰岛素所致,且有一定的遗传倾向.活产婴儿中CHI的发病率为1/30 000～1/50000,而在相对封闭环境内通婚比较高的国家和地区（如阿拉伯地区）CHI的发病率可能高至1/2 500.
作者 罗飞宏
机构地区 复旦大学附属儿科医院内分泌遗传代谢科
出处 《中华儿科杂志》 CAS CSCD 北大核心 2015年第6期468-471,共4页 Chinese Journal of Pediatrics
关键词 先天性高胰岛素血症 分泌胰岛素 诊治 胰岛素过量 胰岛Β细胞 阿拉伯地区 遗传倾向 低血糖
分类号 R587.3 [医药卫生—内分泌]
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参考文献32

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  • 2Mazor-Aronoviteh K, Gillis D, Lobel D, et al. Long-term neurodevelopmental outcome in eonservatively treated congenital hyperinsulinism [ J ]. Eur J Endoerinol, 2007,157 (4) : 491-497.
  • 3Petraitien I, Barauskas G, Gulbinas A, et al. Congenital hyperinsulinism [ J ]. Medicina ( Kaunas), 2014,50 ( 3 ) : 190- 195.
  • 4Bellann6-Chanteiot C, Saint-Martin C, Ribeiro MJ, et aL ABCC8 and KCNJll molecular spectrum of 109 patients with diazoxide- unresponsive congenital hyperinsulinism [ J ]. J M ed Genet, 2010, 47(11 ) : 752-759.
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同被引文献39

  • 1Jaya Sujatha Gopal-Kothapani,Khalid Hussain.Congenital hyperinsulinism:Role of fluorine-18L-3, 4 hydroxyphenylalanine positron emission tomography scanning[J].World Journal of Radiology,2014,6(6):252-260. 被引量：3
  • 2Rahman SA, Nessa A, Hussain K. Molecular mechanisms of congenital hyperinsulinism [J]. J Mol Endocrinol, 2015,54(2) : 119-129.
  • 3Arnoux JB, Verkarre V, Saint-Martin C, et al. Congenital hyperinsulinism: current trends in diagnosis and therapy[J]. Orphanet J Rare Dis,2011,6:63.
  • 4Ustian NU, Dili D, Kundak AA, et al. A novel mutation in ABCC8 gene in a newborn with congenital hyperinsulinism a case report[J]. Fetal Pediatr Pathol, 2013,32(6) :412-417.
  • 5Arya VB, Mohammed Z, Blankenstein O, et al. Hyperinsulinaemic hypoglycaemia[J]. Horm Metab Res,2014, 46(3) : 157-170.
  • 6Petraitien Ct I, Barauskas G, Gutbinas A, et al. Congenital hyperinsulinism[J]. Medicina (Kaunas) ,2014,50(3) : 190-195.
  • 7Su C, Gong C, Sanger P, et al. Long-term follow-up and mutation analysis of 27 Chinese cases of congenital hyperinsulinism [J]. Horm Res Paediatr, 2014, 81 (3) : 169- 176.
  • 8Roenkovd K, Gtiemes M, Shah P, et al. The diagnosis and management of hyperinsulinaemie hypoglyeaemia[J]. J Clin Res Pediatr Endocrinol,2015,7(2) : 86-97.
  • 9Yorifuji T,Masue M,Nishibori H. Congenital hyperinsulinism: global and Japanese perspectives[J]. Pediatr Int, 2014,56 (4) : 467-476.
  • 10James C, Kapoor RR, Ismail D, et al. The genetic basis of congenital hyperinsulinism[J]. J Med Genet, 2009,46 (5) : 289- 299.

引证文献7

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中华儿科杂志
2015年 第6期

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