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甲状腺过氧化物酶抗体和甲状腺球蛋白抗体阳性临界值的确定及其临床意义 被引量：2

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摘要 目的探讨甲状腺过氧化物酶抗体(TPOAb)和甲状腺球蛋白抗体(Tg Ab)阳性临界值的确定及其临床意义。方法 500例健康体检的正常人,测定其TPOAb、Tg Ab及促甲状腺激素(TSH)水平。结果 TPOAb高值95%可信区间上限为37.8 IU/ml,Tg Ab高值95%可信区间上限为38.6 IU/ml。当TPOAb浓度为37.8 IU/ml或Tg Ab浓度为38.6 IU/ml时,TSH升高(>4.8 IU/ml)或TSH降低(<0.3 IU/ml)的比例差异有统计学意义(P<0.05)。结论本次研究认为当TPOAb为37.8 IU/ml及Tg Ab为38.6 IU/ml时可定义为阳性临界值。
作者 郭真 毕经丽
机构地区 潍坊市脑科医院检验科
出处 《中国实用医药》 2015年第13期34-35,共2页 China Practical Medicine
关键词 甲状腺过氧化物酶抗体 甲状腺球蛋白抗体 阳性临界值
分类号 R446.6 [医药卫生—诊断学]
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  • 1彭春霞,张慧敏.睡眠剥夺对健康青年糖代谢的影响[J].中华航空航天医学杂志,2009,20(1):34-36. 被引量：9
  • 2Baloch Z, Carayon P, Comte - Devolx B,et al. Laboratory medicine practice guidelines. Laboratory support for the diagnosis and monito- ring of thyroid disease[ J]. Thyroid, 2003,13 ( 1 ) :3 - 126.
  • 3Clarke NJ,Zhang Y,Reitz RE. A novel mass spectrometry - based as- say for the accurate measurement of thyroglobulin from patient samples containing antithyroglobulin autoantibodies [ J ]. J Investig Med, 2012, 60(8) :1157 - 1163.
  • 4Czarnocka B, Cocks Eschler D, Godlewska M,et al. Thyroid antibod- ies: thyroid pcroxidase and thyroglobulin antibodies [ M ]. Amster- dam : Elsevier, 2014:365 - 373.
  • 5Garber JR, Cobin RH, Gharib H,et al. Clinical practice guidelines for hypothyroidism in adults: cosponsored by the American Association of Clinical Endocrinologists and the America Thyroid Association [ J ]. Endocr Pract ,2012,18 ( 6 ) :988 - 1028.
  • 6Stagnaro - Green A, Abalovich M, Alexander E,et al. Guidelines of the American Thyroid Association for the diagnosis and management of thyroid disease during pregnancy and postpartum[J]. Thyroid,2011, 21(10) :1081 - 1125.
  • 7Jensen EA, Petersen PH, Blaabjerg O,et al. Establishment of refer- ence distributions and decision values for thyroid antibodies against thyroid peroxidase(TPOAb), thyroglobulin (TgAb) and the thyrotro- pin receptor (TRAb) [ J]. Clin Chem Lab Med ,2006,44 ( 8 ) :991 - 998.
  • 8Zophel K, Sailer B, Wunderlich G,et al. Autoantibodies to thyroper- oxidase in a large population of euthyroid subjects: implication for the definition of TPOAb reference intervals [ J ]. Clin Lab, 2003 ( 11 - 12) , 49:591 -600.
  • 9Tozzoli R, Giavarina D, Villalta D,et al. Definition of reference limits for autoantibodies to thyroid peroxidase and thyroglobulln in a large population of outpatients using an indireet method based on current data[J]. Arch Pathol Lab Med,2008, 132(12) :1924-1928.
  • 10Kaloumenou I, Mastorakos G, Alevizaki M,et al. Thyroid autoimmu- nity in schoolchildren in an area with long - standing iodine sufficien- cy: correlation with gender, pubertal stage and maternal thyroid auto- immunity [ J ]. Thyroid,2008, 18 ( 7 ) :747 - 754.

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中国实用医药
2015年 第13期

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