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四物汤对胃癌术后早期营养状态及免疫功能的影响 被引量:12

Effect of Siwu Decoction on Early Nutritional Status and Immune Function of Postoperative Patients with Gastric Cancer
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摘要 目的探讨四物汤对胃癌术后早期营养状态和机体免疫功能的影响。方法将64例经胃镜活检初次诊断为晚期胃癌患者根据治疗方法的不同分为观察组与对照组,每组32例。术后早期均给予肠内营养支持,观察组在此基础上加用四物汤,对照组仅给予等量生理盐水,观察两组患者术后营养指标及免疫功能情况。结果两组患者术后第10天血红蛋白(hemoglobin,Hb)、总胆固醇(total cholesterol,TC)、总甘油三酯(total triglycerides,TG)、低密度脂蛋白胆固醇(low density lipoprotein cholesterin,LDL-C)、CD3、CD4、Ig G、Ig M水平与术前比较差异具有统计学意义(P<0.05),且观察组高于对照组(P<0.05),术后两组不良反应比较差异无统计学意义(P>0.05)。结论术后肠内营养乳剂基础上给予四物汤可以改善胃癌患者术后的营养状态与免疫功能,促进患者康复。 Objective To investigate the effect of Siwu Decoction on early nutritional status and immune function of postoperative patients with gastric cancer. Methods A total of 64 terminal gastric cancer patients initially diagnosed by biopsy of initial diagnosis were divided into observation group (n = 32) and control group (n = 32) according to treatment methods. All the patients were treated with early enteral nutritional support, and then the observation group was added with Siwu Decoction, while the control group was given additional physiological saline of same volume only. The postoperative nutritional indexes and immune function were observed in the two groups. Results The differences in levels of hemoglobin (Hb) , total cholesterol (TC) , total triglycerides (TG) , low density lipoprotein cholesterin (LDL-C), CD3, CD4, IgG and IgM on the postoperative 10^th d were statistically significant, compared with those before the treatment ( P 〈 0. 05 ) , and the levels in observation group were significantly higher than those in control group ( P 〈 0. 05 ) , but the differences in incidence rates of adverse reactions in the two groups after treatment were not statistically significant (P 〉 0. 05). Conclusion Siwu Decoction treatment after enteral nutrition emulsion can improve the nutritional status and immune function and promote recovery of postoperative patients with gastric cancer.
出处 《解放军医药杂志》 CAS 2015年第6期83-86,共4页 Medical & Pharmaceutical Journal of Chinese People’s Liberation Army
基金 (贺瑞麟)全国名老中医药专家传承工作室资助
关键词 胃肿瘤 四君子汤 营养状况 免疫功能 Stomach neoplasms Sijunzi Decoction Nutritional status Immune function
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