摘要
通过查阅29篇文献,对黄蜀葵花的成分、现代临床与药效、体内过程、相关知识产权专利进行归纳总结;该植物所含成分主要为以杨梅素、槲皮素、棉皮素为母核的黄酮类化合物;用于慢性肾脏病、感染创面,具有抑制免疫、抗炎作用;其在体内的代谢过程,以羧基化反应、乙酰化反应、水解反应为主,被动扩散吸收;相关知识产权集中在成分提取、制备工艺、药物配伍方面,涉及疾病集中于慢性肾病方面。现代临床与基础研究对黄蜀葵花的研究与挖掘明显不足。扩大黄蜀葵花适应症,深化基础与临床研究,具有良好前景。本文综述黄蜀葵花近10年来的研究进展,以期为其进一步研究开发提供参考。
The chemical constituents,efficacy,in vivo process and related intellectual property rights on Abelmoschi Corolla were summarized. The main chemical structure types from Abelmoschi Corolla include myricetin,quercetin and gossypetin. It was mainly used for chronic kidney disease and wound infection,with the ability to suppress the immune response and anti-inflammatory effect. The metabolic processes in vivo involved in carboxyl reaction, acetylation reaction, hydrolysis reaction, and absorption by passive diffusion. Intellectual property rights concentrated on compund extraction,preparation and drug compatibility,lacking modern clinical and basic research. This paper reviewed progress on Abelmoschi Corollat,put forward the research idea.
出处
《中国实验方剂学杂志》
CAS
CSCD
北大核心
2015年第13期231-234,共4页
Chinese Journal of Experimental Traditional Medical Formulae
基金
江苏高校优势学科建设工程项目(BL2014100)
关键词
黄蜀葵花
化学成分
药理作用
Abelmoschi Corolla
chemical compasition
pharmacological activity
