摘要
目的探讨进展期胃癌患者围术期应用腹腔热灌注化疗与辅助化疗联合治疗的效果。方法本次选取进展期胃癌患者150例,均为我院2012年5月~2013年5月收治,均行D2＋根治术治疗,随机分组,就胃癌术后全身化疗（对照组,n=70）与围术期得腔热灌注化疗联合辅助化疗（观察组,n=80）效果展开对比。结果两组毒副反应及并发症无明显差异（P〉0.05）,观察组2年复发率低于对照组,3年生存率高于对照组,均有统计学差异（P〈0.05）。结论进展期胃癌围手术期腹腔热灌注化疗联合辅助化疗可降低复发率,提高远期生存率。
Objective Discussion of advanced gastric cancer patients perioperative intraperitoneal hyperthermic perfusion chemotherapy combined treatment with adjuvant chemotherapy. Methods The selected 150 cases of patients with advanced gastric cancer, both in our hospital from May 2012 to May 2013 were treated underwent D2 ＋ radical treatment, randomized, on gastric cancer chemotherapy（control group,n=70） and perioperative chemotherapy was cavity perfusion chemotherapy（observation group, n=80） to start contrast effect. Results Toxicities and complications groups had no significant difference（P〈0.05）, the observation group 2-year recurrence rate was significantly lower than the control group, the 3-year survival rate was significantly higher, were statistically significant（P〈0.05）. Conclusion Advanced gastric perioperative intraperitoneal chemotherapy plus adjuvant chemotherapy can significantly reduce the recurrence rate and improve long-term survival.
出处
《中国继续医学教育》
2015年第15期82-83,共2页
China Continuing Medical Education
关键词
进展期胃癌
围手术期
腹腔热灌注化疗
辅助化疗
Advanced gastric cancer
Perioperative period
Intraperitoneal hyperthermic perfusion chemotherapy
Adjuvant chemotherapy
