摘要
目的:探讨清热复脉汤对痰热型快速型房颤患者中医证候积分、脑钠肽(Brain Natriuretic Peptide,BNP)及动态心电图的影响。方法:将120例痰热型快速型房颤患者随机分为对照组及治疗组各60例,对照组患者按照西医常规治疗,治疗组在对照组基础上加用清热复脉汤,每日一剂,口服。两组疗程均为4周,观察中医证候积分并比较两组治疗前后BNP、动态心电图变化。结果:1.两组治疗后中医证候积分较治疗前均有改善(P<0.01);治疗组中医证候积分改善程度显著优于对照组(P<0.01)。2.两组治疗后BNP均明显下降,治疗组降低BNP水平的程度明显优于对照组(P<0.01);3.两组治疗后动态心电图平均心室率、房颤持续时间均较治疗前明显减少,且治疗组减少平均心室率及房颤持续时间幅度均明显优于对照组(P<0.01)。结论:清热复脉汤能改善痰热型快速型房颤患者的中医证候,有效的降低其BNP,减少平均心室率及房颤持续时间。
Objective：To observe the influence of Qingrefumai decoction on rapid atrial fibrillation with the type of heart-phlegm on TCM symptoms total score ,Brain Natriuretic Peptide（BNP） and Holter. Methods： The study got 120 patients of rapid atrial fibrillation with the type of heart-phlegm and randomly divided them into treatment group and control group. Both groups had 60 cases. The control group was treated with routine Western medicine, while the treatment group was treated with the same therapy as control group, and with the Qingrefumai decoction. Observe the TCM symptoms total score, BNP and Holter of two groups before and after 4 weeks＇ treatmen. Results： 1. After treatment, the TCM symptoms total score of two groups both had significantly improved （both P〈0.01）; the treatment group improved more than the control group, with a significant difference （P〈0.01）. 2. After treatment, the levels of BNP of both groups were lower than before （P〈0.01）, and the extent of the reduction of the BNP levels in the treatment group was more significant than that of the control group （ P〈0.01）; 3. After treatment, both of the average ventricular rate and the duration of atrial fibrillation were significantly different with pretherapy in the two groups （P〈0.01）. The average ventricular rate and duration of atrial fibrillation of treatment group after treatment decreased significantly compared with the control group, with a significant difference （P〈0.01）. Conclusion： Qingrefumai decoction may alleviate the TCM symptoms of rapid atrial fibrillation with the type of heart-phlegm, reduce the blood plasma BNP, as well as improve the clinical effectiveness of Holter.
出处
《内蒙古中医药》
2015年第4期107-108,共2页
Inner Mongolia Journal of Traditional Chinese Medicine
基金
漳州市自然科学基金项目(编号:ZZ2012J36)
