摘要
目的：评价SPECT/CT融合显像对可疑骨转移灶的诊断效能。方法回顾性分析64例恶性肿瘤患者经全身骨显像发现的96个可疑骨转移病灶，对可疑病灶行同机SPECT/CT融合显像，由两名核医学医师分别对SPECT、CT及SPECT/CT融合显像进行分析并评分，以病理学结果或6个月以上复查影像学及临床随访结果作为最终确诊依据。SPECT/CT融合显像对可疑病灶的诊断效能通过受试者工作特征曲线（ROC曲线）进行评价。结果 SPECT/CT显像诊断可疑骨转移灶的灵敏度、特异度、准确率、阳性预测值和阴性预测值分别为93．1%、86．8%、90．6%、91．5%和89．2%；ROC曲线下面积：SPECT/CT融合图像为0．956，CT图像为0．897，SPECT图像为0．710。结论 SPECT/CT融合显像较SPECT及CT显像具有较高的诊断效能。
Objective To evaluate the diagnostic efficacy of single photon emission computed tomography/computed tomography（SPECT/CT） in assessing possible bone metastases. Methods Sixty-four patients with history of primary cancer with 96 lesions that could not be definitively diagnosed using planar scintigraphy were included in this study, and SPECT/CT was performed. SPECT, CT, and SPECT/CT images were independently interpreted and scored by two experienced nuclear medicine physicians. The final diagnosis was confirmed by the pathological results or follow-up （≥6 months ） . The value of additional fused images was assessed using receiver operating characteristic（ROC） analysis. Results The sensitivity, specificity, accuracy, and negative and positive predictive values for SPECT/CT imaging were 93.1%, 86.8%, 90.6%, 91.5%, and 89.2%, respectively. The areas under the ROC curve were 0.956, 0.897, and 0710 for SPECT/CT-fused images, CT images, and SPECT, respectively. Conclusion SPECT/CT fusion imaging was more accurate and valuable compared with separate sets of SPECT and CT images.
出处
《国际放射医学核医学杂志》
2015年第3期201-204,共4页
International Journal of Radiation Medicine and Nuclear Medicine
基金
天津市卫生局科技基金（2013KZl2）
