摘要
目的探讨纳洛酮治疗新生儿肺炎的临床效果。方法选取2013年10月—2014年10月曲沃县人民医院收治的新生儿肺炎患儿108例,随机分为对照组与治疗组,各54例。两组患儿均给予常规治疗,对照组患儿在常规治疗基础上予以地塞米松治疗,治疗组患儿在常规治疗基础上予以纳洛酮治疗。观察两组患儿治疗前后呼吸功能(Pa O2、Pa CO2)、给氧时间、临床疗效及不良反应发生情况。结果治疗前两组患儿Pa O2、Pa CO2比较,差异无统计学意义(P>0.05),治疗后治疗组患儿Pa O2高于对照组,Pa CO2低于对照组,给氧时间短于对照组,总有效率高于对照组,差异有统计学意义(P<0.05);两组患儿不良反应发生率比较,差异无统计学意义(P>0.05)。结论纳洛酮治疗新生儿肺炎的临床效果显著,不良反应小,安全性高。
Objective To explore the effect of naloxone in treating pneumonia of newborn. Methods A total of 108 pneumonia of newborn children were selected in the People＆#39;s Hospital of Quwo County from October 2013 to October 2014,and they were randomly divided into control group and treatment group,each of 54 cases. Both group were given conventional treat-ment,control group were given dexamethasone on the basis of conventional treatment,treatment group were given naloxone on the basis of conventional treatment. Before and after treatment,respiratory function（ PaO2、PaCO2 ）,oxygen time,clinical effect and adverse reactions between two groups were compared. Results Before treatment,PaO2 and PaCO2 showed no signifi-cant differences between the two groups（P＆gt;0. 05）,after treatment,PaO2 of treatment group was higher than that of control group,PaCO2 of treatment group was lower than that of control group,oxygen time of treatment group was shorter that of control group,clinical efficacy rate of treatment group was higher than that of control group（P〈0. 05）,adverse reactions rate showed no significant differences between the two groups（P＆gt;0. 05）. Conclusion Naloxone has notable curative effect in the treat-ment of pneumonia of newborn,has mild adverse reactions and high security.
出处
《临床合理用药杂志》
2015年第15期55-56,共2页
Chinese Journal of Clinical Rational Drug Use
关键词
肺炎
婴儿
新生
纳洛酮
治疗结果
Pneumonia
Infant,newborn
Naloxone
Treatment outcome
