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脑出血并发感染患者血清降钙素原与C反应蛋白水平变化及意义 被引量:3

Change and significance of serum procalcitonin and C-reactive protein levels in cerebral hemorrhage patients complicated with infection
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摘要 目的探讨脑出血患者并发感染血清降钙素原与C反应蛋白水平变化及意义。方法 160例脑出血患者按照感染分为研究组(感染者)和对照组(未感染者)。观察2组患者血清PCT与CRP的水平,并比较2组患者PCT与CRP阳性率、灵敏度、特异度。结果研究组患者的PCT与CRP的水平显著高于对照组(P<0.05);研究组患者的CRP阳性率稍微高于对照组,PCT阳性率显著高于对照组(P<0.05)。血清PCT与CRP阳性率、灵敏度基本相符,血清PCT的特异度显著高于CRP(P<0.05)。结论 PCT与CRP均是检测脑出血后并发感染的有效指标,灵敏度和阳性率均很高,但血清PCT的特异度明显高于CRP。 Objective To explore the change and significance of serum procalcitonin (PCT) and C-reactive protein (CRP) levels in cerebral hemorrhage patients complicated with infec- tion. Methods A total of 160 cerebral hemorrhage patients were divided into research group (patients with infection) and control group (patients without infection). Levels of PCT and CRP were observed in both groups, and the positive rate, sensitivity, specificity of PCT and CRP were compared as well. Results Levels of PCT and CRP in the research group were significantly higher than those in the control group (P 〈 0.05). The positive rate of CRP in the research group was slightly higher than that in the control group, and the positive rate of PCT was significantly higher than the control group (P〈0.05). The positive rates and sensitivity of serum CRP and PCT were similar, and the specificity of serum PCT was significantly higher than the CRP (P 〈 0.05). Con- clusion Serum PCT and CRP are effective indicators for detection of infection after intra-cerebral hemorrhage, the positive rate and sensitivity of PCT and CRP are high, but the specificity of serum PCT is significantly higher than CRP.
出处 《实用临床医药杂志》 CAS 2015年第13期27-29,共3页 Journal of Clinical Medicine in Practice
关键词 脑出血并发感染 血清降钙素原 C反应蛋白 cerebral hemorrhage complicated with infection serum procalcitonin C-reactive protein
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