摘要
目的探讨非小细胞肺癌患者接受胸腔镜根治术(video-assisted thoracoscopic surgery,VATS)和传统腋下小切口根治术(minimal incision thoracotomy,MIT)的近期及远期疗效。方法选取2010年1月-2012年1月新疆医科大学附属肿瘤医院胸外科初治的病理分期I期(UICC2009版)的未接受术后辅助化疗的NSCLC患者,VATS手术75例,MIT手术74例,比较两组在术后恢复相关指标、术后并发症、淋巴结清扫数目以及术后1、2、3年无瘤生存率的差异。结果 VATS组在术中出血量、重症监护时间、首次下床站立时间、平均住院天数均明显少于MIT组(P<0.05)。VATS组术后全身炎性反应明显轻于MIT组(P<0.05)。VATS组1、2、3年无瘤生存期分别为84.3%、68.6%和63.8%,MIT组1、2、3年无瘤生存期分别为72.3%、67.7%和63.1%,差异无统计学意义(P=0.288)。结论胸腔镜手术对于早期非小细胞肺癌患者在术后恢复方面存在明显优势,远期疗效与传统开胸手术效果相当。
Objective To analyze retrospectively the short-term and long-term effects of the stage I non-small-cell lung carcinoma patients who received video-assisted thoracoscopic surgery （VATS）and minimal incision thoracotomy （MIT）from January 2010 to January 2012.Methods We selected VATS 75 cases and MIT 74 cases of initial pathological staging Ⅰ（UICC2009）patients who did not receive postoperative adjuvant chemotherapy,and analyzed the differences between the two groups in postoperative recovery re-lated indicators,postoperative complications,the number of lymphadenectomy and 1,2,3 year disease-free survival rate.Results VATS is less and shorter than MIT （P〈0.05）in intraoperative blood loss, days of intensive care,first standing time and duration of stay in hospital.After dynamic monitoring WBC and PCT,the results showed that the systemic inflammatory reaction of VATS was slighter than that of MIT （P〈0.05）.The 1,2,3 year DFS rates of VATS is 84.3%,68.6 and 63.8%;while the MIT is 72.3%,67.7% and 63.1%,and there was no statistical differences between the two groups （P =0.288）. Conclusion Comparing with MIT,VATS has obvious advantages in postoperation recovery for early stage of NSCLC patients,and has the similar disease-free survival rate in postoperation.
出处
《新疆医科大学学报》
CAS
2015年第7期896-899,共4页
Journal of Xinjiang Medical University
基金
新疆医科大学科研创新基金(XJC201376)
关键词
非小细胞肺癌
外科治疗
胸腔镜
non-small-cell lung carcinoma
surgical treatment
thoracoscope
