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铜绿假单胞菌生物被膜耐药性分析及tolA和ndvB基因检测 被引量：3

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摘要 生物被膜附着于各种环境表面［1］，特别是医疗设备表面及导管表面，导致临床上多种慢性和难治性感染的反复发作［2］。据美国国立卫生研究院统计80％的人类微生物感染均由生物被膜引起。形成生物被膜后，细菌的增长、特异基因的表达和蛋白质的产量发生改变［3-4］，对抗生素的抵抗作用可比浮游菌提高10～1000倍［5］。
作者 李艳华 刘文恩 罗珊 陈伟 钟一鸣
机构地区 中南大学湘雅医院检验科
出处 《中华检验医学杂志》 CAS CSCD 北大核心 2015年第6期416-418,共3页 Chinese Journal of Laboratory Medicine
基金 湖南省教育厅科研基金（湘教通[2012]594号） 湖南省卫生厅课题（B2014-014）
关键词 生物被膜 铜绿假单胞菌 耐药性分析 基因检测 美国国立卫生研究院 医疗设备表 难治性感染 微生物感染
分类号 R446.5 [医药卫生—诊断学]
  • 相关文献

参考文献19

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二级参考文献41

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  • 2倪明,田德英,余冰,皮斌,朱旭慧,张东绅.一株含新的mucA突变基因的黏液型铜绿假单胞菌的生物学特性[J].中华医学杂志,2004,84(19):1649-1653. 被引量：9
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共引文献30

同被引文献30

  • 1Cornelis P, Dingemans J. Pseudomonas aeruginosa adapts its iron uptake strategies in function of the type of infections [ J ]. Front Cell Infect Microbiol, 2013, 3 (3) : 75.
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二级引证文献8

中华检验医学杂志
2015年 第6期

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