摘要
目的探讨血清salusin-β水平与男性吸烟者发生冠心病的相关性。方法 192例男性吸烟者,根据是否罹患冠心病分为2组,罹患冠心病者92例为观察组,未罹患冠心病者100例为对照组。采用ELISA法测定2组血清salusin-β水平并比较,采用logistic回归分析血清salusin-β水平与冠心病的相关性。结果观察组血清salusin-β水平为[5.49（3.56,7.73）ng/L]明显高于对照组[3.24（2.22,4.91）ng/L],差异有统计学意义（P〈0.01）;多变量logistic回归分析显示血清salusin-β水平是男性吸烟者发生冠心病的独立危险因素（OR=1.93,95%CI：1.22-3.04,P=0.002）。结论高血清salusin-β水平与男性吸烟患者发生冠心病有明显相关性。
Objective To explore the relationship between serum salusin-βlevels and coronary heart disease（CHD）in male smokers.Methods A total of 192 male smokers were divided to CHD group（n=92）and non-CHD group（n=100）.The serum salusin-βlevels were determined by ELISA and compared between two groups.The independent correlation between serum salusin-βlevels and CHD was investigated by logistic analysis.Results The serum salusin-βlevel was significantly higher in CHD group（5.49（3.56,7.73）ng/L）than that in non-CAD group（3.24（2.22,4.91）ng/L）（p〈0.01）.Multiple logistic analysis demonstrated that serum salusin-βlevel was an independent risk factor CHD in male smokers（OR=1.93,95%CI：1.22 to 3.04,P=0.002）.Conclusion High serum salusin-βlevel is obviously correlated with CAD in male smokers.
出处
《中华实用诊断与治疗杂志》
2015年第6期595-596,共2页
Journal of Chinese Practical Diagnosis and Therapy
