摘要
目的探究与分析丙基硫氧嘧啶治疗甲状腺功能亢进的临床效果。方法选取我院自2012年1月至2015年2月收治的42例确诊新发甲状腺功能亢进作为研究对象,采取随机数字表法分为甲巯咪唑组与丙基硫氧嘧啶组,每组各21例。观察与对比两组患者治疗结束后,患者临床症状的缓解情况以及药物不良反应的发生率。结果系统治疗后,发现丙基硫氧嘧啶组的总有效率明显优于甲巯咪唑组,组间相比差异显著(χ2=5.67,P<0.05);且丙基硫氧嘧啶组的不良反应发生率明显低于甲巯咪唑组,组间相比差异显著(χ2=5.68,P<0.05)。结论丙基硫氧嘧啶可有效缓解甲状腺功能亢进的临床症状,临床疗效确切,且安全性方面明显优于甲巯咪唑,可作为一种理想方法应用于临床工作中。
Objective To explore and analyze the clinic effect of propylthiouracil on treating hyperthyroidism. Method 42 hyperthyroidism patients admitted in our hospital from January 2012 to February 2015 were selected as research objects, they were divided into methimazole group and propylthiouracil group by random number method, with 21 patients in each group. Observed two groups＇ relief situation and incidence of adverse reaction after treatment. Result After treatment, the efficiency of propylthiouracil group was obvious better than that of methimazole group,the difference between two groups was obvious（χ2=5.67,P〈0.05）; and the incidence of adverse reaction of propylthiouracil group was better than that of methimazole group, the difference between two groups was obvious（χ2=5.68,P〈0.05）. Conclusion Propylthiouracil can relieve symptoms of hyperthyroidism effectively, its clinical effect is exact and it is better than methimazole, which can be as a ideal method in clinical work.
出处
《中国医药指南》
2015年第19期39-40,共2页
Guide of China Medicine
