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介入治疗在CTO的应用及其对预后的影响

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摘要 【目的】探讨冠状动脉慢性完全闭塞病变(CTO)患者经皮冠状动脉介入治疗(PCI)后的临床效果以及影响介入治疗成功的因素。【方法】收集本院心内科2012年6月至2014年6月间经冠状动脉造影示完全闭塞病变的患者568例,其中 CTO 病变284例,186例 CTO 病变患者行 PCI ,观察并记录治疗结果,分析其临床特点和预后。【结果】134例患者闭塞冠脉成功开通(开通组),52例未开通(未开通组),CTO 病变 PCI 成功率为72.0%(134/186);开通组患者平均年龄低于未开通组[(61.9±9.7)岁 vs (66.8±9.9)岁, P <0.05)];开通组患者首次出现症状至治疗的时间低于未开通组[(128.4±201.6)周 vs (182.3±212.4)周,P< 0.05)];开通组患者高血压发生率高于未开通组(73.1% vs 59.6%,P < 0.05);开通组患者高胆固醇史比例高于未开通组(20.1% vs 9.6%,P < 0.05);开通组患者总胆固醇平均含量高于未开通组[(5.1 ± 1.2) mmol/L vs (3.6 ± 1.4)mmol/L , P < 0.05)];随访期内胸痛胸闷者开通组比例低于未开通组(12.6% vs 74.2%,P < 0.05)。【结论】CTO 的介入治疗安全可靠,PCI 成功率与首次出现症状至治疗时间和患者年龄、高血压、血液总胆固醇含量等因素有关,闭塞病变开通者临床预后较好。
出处 《医学临床研究》 CAS 2015年第6期1206-1208,共3页 Journal of Clinical Research
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