摘要
目的探讨牙周炎正畸治疗患者炎性及牙周状态的变化。方法选取2012年12月-2014年4月在本院就诊的152例牙周炎患者作为研究对象,随机分为研究组和对照组,各76例。对照组给予基础治疗,研究组在对照组的基础上给予正畸治疗,比较两组治疗前后的龈沟液、血清炎性细胞因子水平及牙周状态变化。结果研究组治疗后的龈沟液、血清炎性细胞因子hs-CRP、IL-1β、IL-5、IL-8、TNF-α水平显著低于对照组治疗后,差异有统计学意义（P〈0.05）。研究组治疗后的PD、PBI、TM、PI、CAL水平显著低于对照组治疗后,差异有统计学意义（P〈0.05）。结论在牙周炎基础治疗的基础上实施正畸治疗能够有效控制牙周炎症状,改善牙周状态,值得临床推广应用。
Objective To explore the change of inflammatory and periodontal status in orthodontic treatment of periodontitis patients. Methods 152 cases with periodontitis from December 2012 to April 2014 in our hospital were selected and randomly divided into the study group and the control group,76 cases in each group.The control group was given basis therapy,the study group was given orthodontic treatment on the basis of the control group.The level of inflammatory cytokines in gingival crevicular fluid and serum,periodontal status changes in two groups before and after treatment was compared. Results The level of hs-CRP,IL-1β,IL-5,IL-8,TNF-α of gingival crevicular fluid and serum in the study group after treatment was lower than that in the control group after treatment,with significant difference（P〈0.05）.The level of PD,PBI,TM,PI,CAL in the study group after treatment was lower than that in the control group after treatment,with significant difference（P〈0.05）. Conclusion The implementation of orthodontic treatment based in the treatment of periodontitis can effectively control the symptoms of periodontitis,improve periodontal status,it is worthy of clinical promotion and application.
出处
《中国当代医药》
2015年第17期102-104,共3页
China Modern Medicine
关键词
牙周炎
正畸治疗
基础治疗
炎性细胞因子
Periodontitis
Orthodontic treatment
Basic treatment
Inflammatory cytokines
