摘要
目的：探讨宫-腹腔镜联合诊治难治性多囊卵巢综合征合并不孕的必要性和疗效。方法选择多囊卵巢综合征（PCOS）合并不孕患者80例，按随机数字表法分为两组各40例，研究组使用宫-腹腔镜联合诊治，对照组仅单纯使用腹腔镜诊治。比较两组手术前后卵巢、卵泡及血清激素水平变化情况，同时记录两组术后正常排卵率、妊娠率及流产率。结果研究组术后卵泡个数及卵巢体积均较治疗前明显下降，且明显低于对照组，差异均有统计学意义（t ＝3．82、3．80、3．74、3．75，均 P ＜0．05）。研究组术后血清 T、LH 及 LH／FSH 较术前明显降低，且明显低于对照组，差异均有统计学意义（t ＝9．32、4．06、3．80，均 P ＜0.05）。研究组术后正常排卵率、妊娠率及流产率分别为90．0％、62．5％及7．5％，与对照组的72．5％、50．0％及15．0％差异均有统计学意义（χ2＝4．02、4．10、3．90，均 P ＜0．05）。结论宫-腹腔镜联合诊治 PCOS 合并不孕疗效显著，可有效提高患者术后排卵率及妊娠率，并降低自然流产率，值得临床推广应用。
Objective To investigate the effect and necessity of hysteroscopy combined with laparoscopy in the diagnosis and treatment of refractory polycystic ovarian syndrome complicated with infertility.Methods 80 cases of patients with polycystic ovary syndrome （PCOS）combined with infertility were randomly divided into two groups with 40 cases in each group.The testing group used hysteroscopy combined with laparoscopy in diagnosis and treatment while the laparoscopy was only used in the control group.The changes of ovary,ovarian follicles and serum hormone level of the two groups which before and after operation were compared,and the data of postoperative normal ovulation rate,pregnancy rate and abortion rate of the two groups were recorded.Results The follicle number and ovarian volume of the testing group were significantly decreased than that before treatment,and were significantly lower than that of the control group,with statistical difference （t =3.82,3.80,3.74,3.75,all P 〈0.05）.The serum T,LH and LH/FSH of the testing group were significantly decreased than the data before surgery,and were significantly lower compared to the control group with statistical difference （t =9.32,4.06,3.80,all P 〈0.05）.The normal ovulation rate,pregnancy rate and abortion rate of the testing group were significantly higher compared to the control group （90.0%,62.5% and 7.5% vs.72.5%,50% and 15%）χ2 =4.02,4.10,3.90,all P 〈0.05）.Conclusion Hyste-roscopy combined with laparoscopy has an obvious curative effect in the diagnosis and treatment of polycystic ovary syndrome combined with infertility,which can effectively improve ovulation rate and pregnancy rate and reduce the abortion rate,is worthy of clinical application.
出处
《中国基层医药》
CAS
2015年第13期1921-1923,共3页
Chinese Journal of Primary Medicine and Pharmacy
基金
浙江省温州市科技局项目（Y20130138）
