摘要
目的：观察夜戴型角膜塑形镜和框架眼镜治疗青少年近视眼的临床效果。方法收集2012年7月至2014年1月河南省郑州市第一人民医院眼科收治的51例（102只眼）8～18岁近视眼患者的临床资料。采用数字表法随机将患者分为角膜塑形镜组25例（50只眼）和框架眼镜组26例（52只眼）。两组患者的裸眼视力、屈光度和眼轴长度以均数±标准差（ x±s）的形式表示，并采用配对t检验的方法进行组内比较，采用独立样本t检验的方法进行组间比较。结果角膜塑形镜组患者戴镜前的裸眼视力、屈光度及眼轴长度分别为（0.22±0.13），（－4.18±0.62）D，（24.48±0.12）mm；框架眼镜组患者戴镜前的裸眼视力、屈光度及眼轴长度为分别为（0.26±0.18），（－4.16±0.65）D，（24.43±0.13）mm。两组比较，差异均无统计学意义（t1＝－2.22，－1.00，0.61；P＞0.05）。1年后角膜塑形镜组患者的裸眼视力、屈光度及眼轴长度分别为（0.31±0.12），（－4.22±0.68）D，（24.50±0.99）mm；框架眼镜组患者的裸眼视力、屈光度及眼轴长度分别为（0.18±0.13），（－4.58±0.52） D，（24.89±0.71）mm。两组比较，差异均有统计学意义，（t1＝－3.24，－4.27，－5.29；P＜0.05）。戴镜前、后角膜塑形镜组患者的裸眼视力比较，差异有统计学意义（t2＝3.59，P＜0.05）。戴镜前、后角膜塑形镜组患者的屈光度和眼轴长度比较，差异无统计学意义（t2＝0.31，0.14；P＞0.05）。戴镜前、后框架眼镜组患者的裸眼视力、屈光度及眼轴长度比较，差异有统计学意义（t3＝2.54，3.63，4.59；P＜0.05）。角膜塑形镜组患者佩戴期间未出现明显的角膜炎、结膜炎症状，有5例（5只眼）患者出现双眼结膜充血及角膜表层轻度点状荧光素染色，给予氧氟沙星滴眼液及重组牛碱性成纤维细胞生长因子滴眼液滴眼，患者均于3～5d内角膜上皮缺损愈合。框架眼镜组患者未出现并发症。结论角膜塑形镜是一种控制青少年近视眼发展的有效方法，值得推广。
Objective To evaluate the clinical efficacy of orthokeratology （ ortho-k ） lenses and frame glasses in the treatment of adolescent myopia .Methods A total of 51 adolescent patients who presented with myopia to the Department of Ophthalmology ,Zhengzhou First People′s Hospital between July , 2012 and January,2014 were recruited.They were randomly allocated into one of two treatment groups：ortho-k lenses （n=25） and frame glasses （n=26）.Before treatment,uncorrected visual acuity,diopter and axial length were measured and differences between the two groups were analyzed by test .Results Uncorrected vision,dipopter and axial length were （0.22±0.13）,（-4.18±0.62）D and （24.48±0.12）mm, respectively,in the ortho-k lens group and were （0.26±0.18）, （-4.16±0.65）D and （24.43±0.13）mm, respectively,in the frame glass group.After one year treatment,these three variables were （0.31±0.12）, （-4.22±0.68） D and （24.50 ±0.99） mm,respectively,in the ortho-k group and were （0.18 ±0.13）, （-4.58±0.52）D and （24.89±0.71）mm,respectively,in the frame glass group（t1=-3.24,-4.27,-5.29;P＆lt;0.05）.The differences in these variables between treatment groups were not significant before treatment （t2=0.31,0.14;P＆gt;0.05）,but were significant after treatment （t3 =2.54,3.63,4.59;P＆lt;0.05）.In contrast ,no complications occurred in any of the cases in the frame glass group .Conclusions Orthkeratology is an effective method to control the development of mypia in adolescents .
出处
《中华眼科医学杂志（电子版）》
2015年第3期30-33,共4页
Chinese Journal of Ophthalmologic Medicine(Electronic Edition)
