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中国河北地区汉族人群HLA-E基因多态性分析 被引量:3

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摘要 目的通过调查中国河北地区汉族人群人类白细胞抗原-E(HLA-E)等位基因多态性分布情况,为探讨HLA-E基因多态性与疾病的关联奠定基础。方法 HLA-E等位基因多态性分析采用聚合酶链反应-序列特异性引物(PCR-SSP)方法,调查285例中国河北地区汉族正常人群。结果 HLA-E的2个等位基因在这一人群中检测到,分别是HLA-E*0101和HLA-E*0103,分布频率分别是41.05%和58.95%。而HLA-E*0104等位基因未检测到。结论中国河北地区汉族人群中共有2个HLA-E等位基因分布,分别为HLA-E*0101和HLA-E*0103,其分布频率相近,分别是41.05%和58.95%。
出处 《广东医学》 CAS 北大核心 2015年第11期1675-1677,共3页 Guangdong Medical Journal
基金 河北省高等学校科学研究计划项目(编号:Z2011208) 河北省张家口市2013年度科学技术研究与发展计划自筹经费项目(编号:1321062D)
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参考文献15

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