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肾功能不全患者抗感染治疗的个体化方案制定 被引量:7

Design individual dosage regimen of infection therapy in renal dysfunction patients
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摘要 目的探讨肾功能不全患者抗感染治疗的个体化方案制定以及临床药师的作用。方法本文通过分析2例临床药师参与的肾功能不全患者抗感染治疗个体化方案的制定过程,探讨肾功能不全患者抗生素治疗中剂量方案制定的难点和重点,从而为此类特殊患者提供药学监护的实践经验。结果与结论 2位患者恢复正常,予以出院。临床医师需要临床药师参与肾功能不全患者抗感染治疗的个体化方案制定。多学科交叉合作有助于提高患者药物治疗的有效性和安全性。 Objective To investigate the approach to design dosage regimens of infection therapy in renal dysfunction patients according to dealing with clinic cases.Methods Clinical pharmacist took part in designing optimal dosage regimens for two renal dysfunction patients,and therefore to investigate the key points for these patients.Clinical pharmacists accumulate practical experiences through this process.Results and Conclusion Two patients returned to normal,to be discharged.Clinical physicians need clinical pharmacists to take part in designing optimal individual regimens for renal dysfunction patients.Multiple disciplines cooperation is helpful to improve the efficacy and safety of medication treatment for patients.
出处 《中国临床药理学杂志》 CAS CSCD 北大核心 2015年第13期1299-1301,共3页 The Chinese Journal of Clinical Pharmacology
基金 北京大学第三医院科研基金资助项目(77476-01)
关键词 肾功能不全 肾功能衰竭 抗感染治疗 个体化方案制定 renal dysfunction renal failure anti-infection therapy individual dosage regimen design
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  • 1ASHP statement on pharmaceutical care [J]. Am J Pharm, 1993, 50 : 1720 - 1723.
  • 2Zhou QT, He B, Zhang C, et al. Pharmacokinetics and pharmacody- namics of meropenem in elderly chinese with lower respiratory tract infections: population pharmacokinetics analysis using nonlinear mixed- effects modelling and clinical pharmacodynamics study [ J ]. Drugs Aging, 2011,28:903 - 912.
  • 3吴华.透析患者抗生素应用的原则[J].中国血液净化,2006,5(11):792-794. 被引量:10

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