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缺血性卒中侧支循环的研究进展 被引量:23

Highlighting the importance of collateral circulation in ischemic stroke
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摘要 侧支循环是近年来缺血性卒中的研究热点之一,它是体内的一种代偿循环,目前分为三级,受先天解剖、后天血流动力学、体液因素等受多种因素的影响。侧支循环在急性缺血性卒中的防治中发挥着重要作用。良好的侧支循环可有效降低卒中发生后神经功能缺损的程度并改善预后。对侧支循环进行分级和合理评估,对判定急性缺血性卒中事件的预后和转归、指导制定个体化治疗方案具有重要意义。随着影像学技术的不断发展,侧支循环评估的准确率大幅度提高,为临床带来便捷。人为促进、干预侧支循环形成也成为卒中治疗的一项新的手段。 Collateral circulation is one of the topics most frequently discussed over recent years. It is, as commonly graded into 3 levels, compensatory circulation in the body and affected by pre-existing anatomy, hemodynamic at the moment, and humoral factors. A good collateral supply may effectively alleviate the neurofunctional deficits after stroke and improve the outcome. Therefore, an establishment of collateral circulation plays a pertinent role in alleviating disability after an acute ischemic stroke. The status of collateral circulation after a stroke may have several prognostic implications, therefore an appropriate grading and evaluation may help to assess the clinical outcomes after acute ischemic stroke, and in directing individualization of treatment regimen. With development of neuroimaging modalities, the accuracy in evaluation of the status of collateral circulation has been significantly improved, thus facilitating improvement in the treatment of stroke. In this regard, to improve collateral circulation is an indispensible therapeutic strategy in the treatment of stroke.
出处 《解放军医学杂志》 CAS CSCD 北大核心 2015年第6期427-432,共6页 Medical Journal of Chinese People's Liberation Army
基金 辽宁省科技攻关计划(2013225089)~~
关键词 侧支循环 卒中 预后 collateral circulation stroke prognosis
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