摘要
随着对胃食管反流病(gastroesophageal reflux disease,GERD)及其危害性认知的逐渐深入,GERD的疾病概念本身及治疗方法也发生革命性的变化。质子泵抑制剂的应用是GERD内科治疗的一个里程碑,而腹腔镜胃底折叠术和胃镜下食管下括约肌射频术的应用使GERD的治疗进入综合性治疗时代,胃镜下食管下括约肌射频治疗对于GERD的典型症状有良好的近、远期疗效,该技术进入中国后被成功应用于高位反流引起的食管外症状,且该技术较抗反流手术具有更简单和微创的特点,有广阔的应用前景。
[Summary] As the gradual deepening understanding of gastroesophageal reflux disease ( GERD ) , more extraesophageal symptoms are noted .The concept and therapeutic strategy for GERD has also undergone a quiet revolution over recent years .The application of proton pump inhibitor ( PPI) has been a landmark of medical treatment for GERD , and the invention of laparoscopic fundoplication and endoscopic radiofrequency energy delivery to the lower esophageal sphincter are marking a new era of comprehensive therapy for GERD .Good short and long term outcomes have been obtained since endoscopic radiofrequency energy delivery to the lower esophageal sphincter was applied on typical symptoms of GERD .Furthermore, the technique has also been successfully used in treating extraesophageal symptoms induced by proximal reflux in China .With more simple and less invasive features compared with anti-reflux surgery, the radiofrequency procedure has broad application prospects .
出处
《中国微创外科杂志》
CSCD
北大核心
2015年第6期558-562,共5页
Chinese Journal of Minimally Invasive Surgery
基金
首都临床特色应用研究(项目编号:Z141107002514109)
关键词
胃食管反流病
胃食管喉气管综合征
食管下括约肌射频术
Gastroesophageal reflux disease
Gastroesophago-larygotracheal syndrome
Radiofrequency energy delivery to the lower esophageal sphincter