摘要
目的对复方樟柳碱联合降糖药物治疗血管性假性视乳头炎的可行性及依从性进行研究,为临床治疗提供指导。方法选取我院2013年3月至2014年3月间治疗的糖尿病伴血管性假性视乳头炎患者124例(124只眼)为研究对象,采用随机抽签的方式将其分为两组,每组62例。对照组研究对象予以复方樟柳碱治疗;观察组研究对象采用复方樟柳碱联合降糖药物阿卡波糖片进行治疗。治疗后就其疗效、安全性及治疗依从性进行组间比较。结果观察组研究对象的总有效率为90.3%高于对照组77.4%的总有效率,且具有显著差异性(P<0.05);观察组研究对象的不良反应发生率为12.9%低于对照组14.5%的不良反应率,但无显著差异性(P>0.05);在治疗依从性的比较中,两组研究对象均在90.0%以上,无显著差异性(P>0.05)。结论复方樟柳碱联合降糖药物用于血管性假性视乳头炎的治疗中具有疗效显著,安全性高,治疗依从性高等优势。
Objective To study the feasibility and compliance of compound anisodine combined with acarbose for the treatment of vascular pseudo papillitis,and to provide guidance for clinical management. Methods The subjects of this study were 124 patients with diabetic vascular pseudo papillitis who were treated in our hospital between March 2013 and March 2014. Patients randomly received compound anisodine alone （control）or combined with acarbose （observation group）. The efficacy,safety and compliance of the treatments were compared between the two groups. Results In the ob-servation group,the overall efficiency was 90. 3%,significantly higher than that of control group （77. 4%;P 〈 0. 05）. Rate of adverse reaction was 12. 9%,lower than that of control group 14. 5% but did not reach statistical significance. Compliance were more than 90% in both groups and there was no difference between the two groups （P 〉 0. 05）. Conclu-sion Compound anisodine combined with acarbose is an effective and safe treatment for vascular pseudo papillitis in dia-betic patients. This regimen also showed great compliance among the patients.
出处
《临床眼科杂志》
2015年第3期224-226,共3页
Journal of Clinical Ophthalmology
关键词
复方樟柳碱
胰激肽原酶肠溶片
血管性假性视乳头炎
可行性
安全性
Compound anisodine
Pancreatic kininogenase enteric coated tablets
Vascular pseudo papillitis
Feasibility
safety
