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铁元素与妊娠期糖尿病相关性研究 被引量:3

Study on relationship between iron and gestational diabetes mellitus
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摘要 目的:评定中孕早期血清铁蛋白水平对妊娠期糖尿病预测的价值。方法:选择孕中15~19周的孕妇18850例,检测血清铁蛋白及空腹血糖。于24~26周行75gOGTT试验,同时检测血清铁蛋白及糖化血红蛋白。用最新标准(IADPSG标准)诊断妊娠期糖尿病,比较妊娠期糖尿病组(GDM,n=1086),对照组(n=1086)组间各个期的血清铁蛋白水平。结果:GDM组与对照组孕妇的年龄、身高、体重、BMI、平均筛查孕周及孕中期HB水平比较,差异均无统计学意义,中孕早期血清铁蛋白(SF)水平与GDM发生有关,SF水平每升高一个单位发生GDM的风险增加0.7%。结论:中孕早期SF水平与GDM发生有关,但中孕早期测定SF水平来预测GDM价值不大。 Objective :To evaluate the level of serum ferritin in the early stages of pregnancy for gestation‐al diabetes prediction value .Methods :Choice of pregnant women (15~19) in the week of gestation ,the detection of serum ferritin and fasting glucose .In 24~26 go 75 g OGTT test ,at the same time detection of serum ferritin ,and glycosylated hemoglobin .With the latest standard (IADPSG) in the diagnosis of gestational diabetes ,the compari‐son between gestational diabetes and normal pregnant women group serum ferritin level of each period .Results :GDM group and control group of pregnant women average age ,height ,weight ,BMI ,screening for gestational age and mid pregnancy HB level comparison ,there were no statistically significant difference ,SF levels in the early sta‐ges of pregnancy associated with GDM happen ,SF levels for every rise in unit had 0 .7% increased risk of GDM . Conclusion :Although SF levels in the early stages of pregnancy associated with GDM occur ,but in the determina‐tion of SF levels in the early stages of pregnancy to predict the GDM of little value .
出处 《陕西医学杂志》 CAS 2015年第7期809-811,共3页 Shaanxi Medical Journal
关键词 糖尿病 妊娠/病理生理学 铁蛋白类/血液 Diabetic,Gestational/physiopathology Ferritins/blood
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参考文献7

  • 1Afkham-Ardekani M,Rashidi M.Iron status in women with and without gestational diabetes mellitus[J].J Diabetes Complications,2009,23:194-198.
  • 2Rajpathak SN,Crandall JP,Wylie-Rosett J,et al.Therole of iron in type 2diabetes in humans[J].Biochim Biophys Acta,2009,1790:671-681.
  • 3贺木兰,蒋静,程海东.中孕早期血清铁蛋白水平对妊娠期糖尿病的预测价值[J].中华围产医学杂志,2011,14(12):753-755. 被引量:10
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二级参考文献17

  • 1YANGHui-xia GAOXue-lian DONGYue SHIChun-yan.Analysis of oral glucose tolerance test in pregnant women with abnormal glucose metabolism[J].Chinese Medical Journal,2005(12):995-999. 被引量:15
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