摘要
丹参酮ⅡA是丹参中有效成分的一种,是发挥其药理活性的基础。丹参酮ⅡA具有增加冠状动脉血流量、改善心肌、降低血小板聚集等功能,在临床上广泛应用于心脑血管疾病的治疗。其抗肿瘤、抗氧化、抗炎以及抗菌等多种生物学活性也扩大了丹参酮ⅡA的应用范围,具有良好的应用前景。该文对丹参酮ⅡA的药理作用以及临床应用的情况作了综述。
Tanshinone Ⅱ A, one of the mainly active ingredients from Salvia miltiorrhiza Bge,is the basis of its pharmacological activity. Tanshinone Ⅱ g can increase the coronary blood flow,improve the myocardial function,reduce platelet aggregation, etc,therefore it is widely used in clinical treatment of eardio-cerebral blood vessel diseases. Because tanshinone Ⅱ g has various biological activities, such as anti-tumor, antioxidant, anti-inflammatory and antibacterial, these actions could enlarge its range of applications. In this review, the pharmacological actions and clinical applications of tanshinone Ⅱ gwere summarized.
出处
《神经药理学报》
2014年第5期55-64,共10页
Acta Neuropharmacologica
关键词
丹参酮ⅡA
药理作用
治疗应用
tanshinone Ⅱ A
pharmacological actions
therapeutic applications
