摘要
目的探讨内镜下氩离子凝固术（APC）治疗胃低级别瘤变的有效性及安全性。方法回顾性分析2013年10月至2014年6月在解放军总医院消化内镜中心行胃镜检查，病理证实为胃低级别瘤变患者的临床资料。的临床资料，将其分为两组：黏膜下注射组（先黏膜下注射亚甲蓝或生理盐水，再APC）和直接APC组，行氩气烧灼术，术后采用Wang—Baker面部表情量表进行疼痛评分，治疗1个月后进行内镜及病理组织学复查。两组治疗有效率的比较采用卡方检验。结果50例患者纳入研究，44例返院复查，36例无残留，治疗有效率为81．8％，黏膜下注射组和直接APC组治疗有效率差异无统计学意义（P值为0．6765）。3例（9．4％）原治疗部位形成溃疡，其余为不同程度瘢痕。所有患者无一例出现出血，穿孔等并发症，术后疼痛评分大多分布在2～6分。2种治疗方法结果比较。结论内镜下氩离子凝固术治疗胃低级别瘤变安全有效、疼痛小、可在门诊进行。
Objective To evaluate the efficacy and safety of argon plasma coagulation （APC） for gastric low-grade intraepithelial neoplasia （LGIN） . Methods We selected retrospectively patients with gastric low-grade intraepithelial neoplasia in our hospital and performed APC under endoscopic. And we separated the patients into two groups： the submucosal injection group （ Normal saline or methylene blue was injected into the submucosa under the lesion before APC, then APC was performed to the lesion ） and direct APC group. Pain score were recorded by using Wang-Baker facial pain scale. A month later, patients underwent regular endoscopy follow-ups. Chi-square test was used to compare the efficient of two groups. Results A total of 50 patients were included in the study from October 2013 through June 2014. Fourty-four patients underwent endoscopy follow-ups after one month and the effective ratio of the treatment was 81.8% （36/44）, which were no significant differences in 2 groups （P=0.6765）. There were 3 cases （9.4%） with ulcer, the rest of the performance for different degree of scarring. There were no treatment-related complications, such as bleeding or perforation. Postoperative pain score mostly distributed in 2 to 6 points. Conclusion APC is considered to be safe and effective, less painful and can be performed in the outpatient service.
出处
《中华胃肠内镜电子杂志》
2014年第1期3-6,共4页
Chinese Journal of Gastrointestinal Endoscopy(Electronic Edition)
关键词
内窥镜检查
胃肿瘤
氩离子凝固术
Endoscopy
Stomach neoplasms
Argon plasma coagulation
