摘要
目的研究不同临床类型功能性便秘(FC)的胃动力情况及与幽门螺杆菌感染(Hp)的关系。方法依据罗马ⅢFC诊断标准,收集2011年12月至2014年3月到内蒙古医科大学消化内科门诊就诊和住院的80例FC患者,对80例FC患者进行结肠传输时间检查,依据检查结果分为3组:慢传输型(STC)、出口梗阻型(OOC)和混合型(MC),健康体检者为对照组;STC、OOC、MC,对照组分别进行胃动力及幽门螺杆菌检查,对比研究不同类型FC患者的胃动力及Hp感染情况,同时探讨Hp与胃动力的关系。结果 STC的半排空时间、延迟相时间、胃排空系数分别为(178.6±35.4)min、(131.5±22.3)min、2.8±0.5;OOC的半排空时间、延迟相时间、胃排空系数分别为(172.2±56.1)min、(128.8±37.1)min、3.1±0.2;MC的半排空时间、延迟相时间、胃排空系数分别为(169.5±42.1)min、(127.7±45.1)min、3.2±0.7;对照组的半排空时间、延迟相时间、胃排空系数分别为(124.7±16.7)min、(81.8±11.8)min、3.6±0.3,STC、OOC、MC与对照组比较,统计分析得t_1=2.368,t_2=2.121,t_3=2.103,P<0.05。STC 33例,Hp阳性16例(48.5%),Hp阴性17例(51.5%);OOC 23例,Hp阳性10例(43,5%),Hp阴性13例(56.5%);MC 24例,Hp阳性11例(45.8%),Hp阴性13例(54.2%);对照组Hp阳性9例(45.0%),Hp阴性11例(55.0%),各组间Hp感染情况差异无统计学意义,P>0.05。结论 STC、OOC、MC存在胃排空延迟;不同临床类型的FC患者Hp感染情况与胃动力变化无明显相关。
Objective To study stomach dynamic conditions of different clinical types of functional constipation and the relationship with helicobacter pylori infection.Methods Eighty cases of FC patients who conform to Rome Ⅲ standard were from outpatient and inpatient in our hospital from 2011 December to 2014 March.Eighty cases of FC patients were divided into on STC、OOC and MC by colon transmission time inspection,healthy cases who have,ot digestive symptoms are as control group after check-up,the above FC patients and the control group are tested gastric emptying time by 13C octanoic acid breath test（OBT）, tested Hp by 13 C-urea breath tests at the same time,in order to explore gastric dynamics and helicobacter pylori of different types of FC and Hp infection,discuss the relationship between Hp,FC and gastric dynamics.Results Half emptying time,phase delay time and gastric emptying coefficient of STC are （178.6 ±35.4）min、（131.5 ±22.3）min、2.8 ±0.5;its of OOC are （172.2 ±56.1 ）min、（128.8 ± 37.1）min、3.1 ±0.2;its of MC are （169.5 ±42.1）min、（127.7 ±45.1）min、3.2 ±0.7;its of the control＆amp;nbsp;group are （124.7 ±16.7）min、（81.8 ±11.8）min、3.6 ±0.3.Compared with the control group,STC、OOC、MC have significantly delayed about gastric emptying（t1 =2.368,t2 =2.121,t3 =2.103,P ＆lt;0.05 ）. 33 cases of STC,16 cases of Hp positive （48.5%）,17 cases of Hp negative （51.5%）;23 cases of OOC, 10 cases of Hp positive （43.5%）,13 cases of Hp negative （56.5%）;24 cases of MC,11 cases of Hp positive（45.8%）,13 cases of Hp negative （54.2%）;20 cases of control group,9 cases of Hp positive （45.0%）,11 cases of Hp negative （55.0%）,Hp infection rate among all group is the same,no statistical significance （P ＆gt;0.05）.Conclusion STC、OOC、MC are delayed about gastric emptying,Hp infection rate in different clinical types of functional constipation is the same.
出处
《中华胃肠内镜电子杂志》
2014年第2期19-22,共4页
Chinese Journal of Gastrointestinal Endoscopy(Electronic Edition)
关键词
功能性
便秘
幽门螺杆菌
胃动力学
Functional
Constipation
Helicobacter pylori
Gastric dynamics
