摘要
目的分析青春期多囊卵巢综合征患者的临床和内分泌代谢特征,寻求早期诊断的依据。方法选择青春期多囊卵巢综合征患者60例。问卷调查月经史,并进行临床特征评分及内分泌、代谢指标测定。结果月经紊乱者100%,肥胖者占48.3%,多囊性卵巢(PCO)者占83.3%,IR者占58.3%。IR组多毛、痤疮、高雄激素表现及肥胖发生率显著高于非IR组,肥胖PCOS患者IR发生率显著高于非肥胖PCOS。结论青春期多囊卵巢综合征患者多伴有月经紊乱、PCO、中心性肥胖、IR、高雄激素血症等特征。
Objective To analyze the clinical and endocrine metabolism features of adolescence polycystic ovarian syindrome,so as to seek basis for early diagnosis. Methods Sixty cases of adolescence PCOS were selected. All cases were evaluated for their clinic manifestations,reproductive endocrine and metabolic parameters. Results 100% of the adolescence PCOS suffered abnormal menstruation,48. 3% of them had obesity,83. 3% of them had polycystic ovaries( PCO) and 58. 3% of them had IR. The prevalence of hirsutism,acne and obesity was significantly higher in IR group than those in non-IR group( P〈0. 01). Conclusions Most of adolescence PCOS accompany with menstrual disorders,PCO,central obesity,IR and hyperandrogenism. IR is correlated with hyperandrogenism and obesity,forming a vicious cycle of endocrinal metabolism.
出处
《齐齐哈尔医学院学报》
2015年第18期2741-2742,共2页
Journal of Qiqihar Medical University
基金
珠海市医药卫生科技计划项目(2012056)
关键词
青春期
多囊卵巢综合征
临床特征
内分泌代谢特征
Adolescence
Polycystic ovarian syindrome
Clinical features
Endocrine metabolism features