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术前放化疗对低位直肠癌患者临床疗效及预后的影响 被引量：8

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摘要 目的探讨术前放化疗对低位直肠癌患者疗效、术后并发症及T淋巴细胞的影响。方法回顾性分析108例低位直肠癌患者的临床资料,将接受术前放化疗的患者作为实验组,术前未接受放化疗的患者作为对照组。全部病例均行直肠癌根治术,两组患者术前、术后均给予相同的营养支持治疗。比较两组患者所用手术时间、出血量、保肛率、术后并发症的发生情况,采用流式细胞仪检测两组患者手术前后血清中T细胞亚群水平的变化。结果两组患者平均手术时间、术中出血量、术后并发症发生率、手术前后血清T细胞亚群的百分率均无统计学差异(P>0.05),但实验组保肛率显著高于对照组(P<0.05)。结论术前放化疗能够明显提高低位直肠癌患者的保肛率,而且不会增加手术难度和术后并发症的发生率,对机体免疫功能也无影响,是一种安全、有效、合理的辅助治疗方法。
作者 吴亮 叶锋
机构地区 浙江省杭州市余杭区妇幼保健院外科 浙江大学附属第一医院肛肠外科
出处 《中国医刊》 CAS 2015年第7期95-97,共3页 Chinese Journal of Medicine
关键词 低位直肠癌 术前放化疗 T淋巴细胞亚群 保肛率
分类号 R735.37 [医药卫生—肿瘤]
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共引文献155

同被引文献66

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引证文献8

二级引证文献9

中国医刊
2015年 第7期

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