摘要
目的应用Orbscan-Ⅱ眼前节分析系统探讨飞秒激光辅助的准分子激光原位角膜磨镶术(femtosecond laser in situ keratomileusis,Fs-LASIK)和飞秒激光小切口透镜切除术(small incision lenticule extraction,SMILE)术后角膜后表面高度的变化。方法前瞻性随机对照研究。选择2014年5月至11月于我院行激光角膜屈光手术的近视患者(等效球镜度数≤-6.00 D)60例(119眼),随机分成A、B两组,每组30例(A组59眼,B组60眼)。A组施行SMILE,B组施行Fs-LASIK,观察术后视力、屈光度等的变化。采用Orbscan-Ⅱ眼前节分析仪,分别于术前、术后1个月对术眼进行眼前节图像采集,记录角膜后表面Diff值变化并进行对比。结果术后1个月两组患者裸眼视力均比术前提高,但两组间相比差异无统计学意义(P>0.05)。术前最佳矫正视力与术后1个月相比差异均无统计学意义(均为P>0.05),术后最佳矫正视力两组间相比差异亦无统计学意义(P>0.05)。术前及术后1个月A、B两组屈光度相比差异均无统计学意义(均为P>0.05)。两组后表面Diff值均较术前显著增加,其中A组术前、术后分别为(0.027±0.001)mm和(0.059±0.001)mm(P<0.05);B组术前、术后分别为(0.029±0.001)mm和(0.054±0.002)mm(P<0.05),但A、B两组术后角膜后表面Diff值增加量相比差异无统计学意义(P>0.05)。结论SMILE和Fs-LASIK矫正近视均安全有效,术后1个月角膜后表面高度均部分前移,其远期变化有待进一步探索。
Objective To explore the posterior corneal surface elevation after small incision lenticule extraction（ SMILE） and femtosecond LASIK（ Fs-LASIK） by Orbscan II anterior analysis system. Methods Randomized controlled study. Sixty cases of myopic patients（ 119 eyes）operated with laser corneal refractive in our hospital from May to November in 2014（ spherical equivalent degree was ≤- 6. 00 D） were selected and randomly divided into group A and group B,30 patients in each group（ 59 eyes in group A and 60 eyes in group B）. Group A underwent SMILE,and group B with Fs-LASIK. The postoperative visual acuity and diopter were observed.With Orbscan-II Scheimpflug imaging system,the anterior segment image were collected at 1month before and after the surgery respectively,the changes of the Diff value of posterior corneal surface were compared and analyzed. Results The postoperative uncorrected visual acuity in group A and group B at postoperative 1 month all improved,but no statistical difference between two groups was found（ P〉0. 05）. The best corrected visual acuity at postoperative 1 month in two groups had no statistical difference compared with the pre-operation（ all P〉0. 05）,and the statistical difference between two groups was found（ P〉0. 05）. The preoperative and postoperative 1 month diopter between two groups had no statistical difference（ all P〉0. 05）. The postop-erative Diff values of posterior corneal surface of the two groups were increased significantly,which in group A were（ 0. 027 ± 0. 001） mm and（ 0. 059 ± 0. 001） mm（ P〈0. 05）,group B were（ 0. 029 ± 0. 001） mm and（ 0. 054 ± 0. 002） mm（ P〈0. 05）. The increased amount for postoperative posterior corneal height between group A and group B showed no statistical significance（ P〉0. 05）. Conclusion SMILE and Fs-LASIK are safe and effective for myopia. The posterior corneal surface elevation is significantly increased at postoperative 1 month,and the changes later need to be explored further.
出处
《眼科新进展》
CAS
北大核心
2015年第7期679-682,共4页
Recent Advances in Ophthalmology
关键词
飞秒激光
小切口透镜切除术
LASIK
角膜后表面高度
femtosecond laser
small incision lenticule extraction
LASIK
posteri-or corneal surface elevation
