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急性冠状动脉综合征并缺血性脑卒中与血清细胞因子的关系

Clinical diagnose and treatment of acute coronary syndrome complicated by cerebral ischemic stroke
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摘要 目的分析急性冠状动脉综合征合并缺血性脑卒中的临床治疗效果。方法选取2012-03—2013-05我院诊治的120例伴缺血性脑卒中急性冠状动脉综合征患者,均在药物治疗前12h及药物治疗2个疗程后,空腹采集静脉血检测细胞因子,观察治疗前后血清细胞因子的变化,观察临床治疗效果。结果药物治疗后,血清细胞因子IL-18、hs-CRP、干扰素-γ等细胞因子的水平产生显著变化,治疗前后的细胞因子水平有显著性差异(P<0.05),总有效率94.2%。结论通过药物治疗,显著改变了伴缺血性脑卒中急性冠状动脉综合征患者的细胞因子水平,获得较好的临床效果,值得临床推广使用。 Objective To investigate the clinical therapeutic effects of acute coronary syndrome complicated by cerebral ischemic stroke.Methods A total of 120 patients with acute coronary syndrome complicated by cerebral ischemic stroke diagnosed and treated in our hospital between March 2012 and May 2013 were selected,and the venous bloods were collected from all the patients on empty stomachs at 12 hbefore the treatments for cell factor determination.After 2courses of treatments,the venous bloods were collected from the 120 patients on empty stomachs for cell factor determination;the changes in serum cell factor level before and after the treatments were observed,and the clinical therapeutic effects on the 120 patients were observed and analyzed.Results In the patients with acute coronary syndrome complicated by cerebral ischemic stroke,after medicinal treatments,serum levels of cell factors such as IL-18,hs-CRP,and interferon-γchange significantly,and the difference in cell factor level before and after the treatments was statistically significant(P〈0.05).After the medicinal treatments,the total effective rate in the 120 patients was 94.2%.Conclusion Medicinal treatments significantly change the cell factor levels and obtain good clinical therapeutic effects in patients with acute coronary syndrome complicated by cerebral ischemic stroke,and consequently are worthy of clinical application.
作者 陈刚
出处 《中国实用神经疾病杂志》 2015年第15期24-25,共2页 Chinese Journal of Practical Nervous Diseases
关键词 急性冠状动脉综合征 缺血性脑卒中 细胞因子 Acute coronary syndrome Cerebral ischemic stroke Cell factor
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