摘要
目的探讨妊娠早期单纯性甲状腺自身抗体阳性与妊娠晚期出现不良妊娠结局的相关性。方法选取2014年6月至12月在行产前检查的86例妊娠早期孕妇作为研究对象,其中43例甲状腺过氧化物酶抗体(TPOAb)阴性的孕妇作为对照组,43例单纯性TPOAb阳性的孕妇作为试验组,比较两组孕妇妊娠晚期的甲状腺功能异常率及不良妊娠结果发生情况。结果试验组孕妇甲状腺功能异常率为27.9%,明显高于对照组的11.6%,差异有统计学意义(P<0.05);试验组孕妇的不良妊娠率为41.9%,明显高于对照组的18.6%,差异有统计学意义(P<0.05)。结论妊娠早期单纯性甲状腺自身抗体阳性的孕妇在妊娠晚期出现不良妊娠结果的发生率较高,应给予高度重视,及时筛查并予以相关治疗。
Objective To explore the relationship between early pregnancy with positive thyroid autoantibodies in late pregnancy and adverse pregnancy outcomes.Methods From 2014 June to 2014 December in our hospital for prenatal examination of 86 cases of early pregnant women as the research object,including 43 cases of thyroid peroxidase antibody（TPOAb）negative pregnant women as control group,simple TPOAb positive pregnant women 43 cases as experimental group,thyroid function were compared between the two groups of pregnant women in late pregnancy and abnormal rate,the incidence of adverse pregnancy outcomes.Results The abnormal rate of group maternal thyroid function test was 27.9%,significantly higher than the control group 11.6%,the difference was statistically significant（P〈0.05）;the experimental group of pregnant women with adverse pregnancy rate was 41.9%, significantly higher than the control group 18.6%,the difference was statistically significant（P〈0.05）.Conclusion Pregnant women early simple thyroid autoantibody positive pregnancy adverse pregnancy results in late pregnancy risk,should be given high priority,timely screening and treated.
出处
《中国药物经济学》
2015年第7期101-103,共3页
China Journal of Pharmaceutical Economics
