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儿童可逆性胼胝体压部病变综合征MRI诊断及鉴别诊断 被引量:2

MRI features of reversible splenium lesion syndrome in children
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摘要 目的探讨儿童可逆性胼胝体压部病变综合征(RESLES)的临床与MR影像学特征。方法搜集我院2013年1月-2015年3月期间经临床确诊并行MRI扫描10例患儿,其中男8例,女2例,年龄1岁2个月-8岁5个月,中位年龄2.8岁。采用1.5 T或3.0 T MR机对10例MERS患儿影像学特点及临床资料进行总结分析。结果 MR初次检查10例患儿病灶部位局限于胼胝体压部呈椭圆形或斑片状,MRI表现:7例病灶呈T1WI稍低信号,3例为等信号、T2WI上2例等信号,8例稍高信号;10例FLAIR为稍高信号影;10例DWI呈明显高信号,相应表观扩散系数(apparent diffusion coefficient,ADC)序列上呈低信号。10例患儿于6-30 d内复查DWI上高信号病灶完全消失。结论 RESLES无特征性临床症状与体征,一般预后良好,MRI上以胼胝体压部可逆性异常信号变化为其特点。MRI能为临床诊断及鉴别诊断提供重要依据,避免不适当的临床处理。 Objective To study the MRI findings in children with reversible splenium lesion syndrome. Methods From January 2013 through March 2015, 10 children(8 boys, 2 girls; age range : 1.2-8.5 years, median age : 2.8 years) with reversible splenium lesion syndrome underwent MRI using a 1.5T or 3.0T scanner. Results MRI of 10 patients showed oval or patchy lesions in the splenium of the corpus callosum that were slightly T1-hypointense(7) or T1-isointense(3), T2-isointense(2) or slightly T2-hyperintense(8), slightly high signal intensity on FLAIR-weighted images(10) and reduced diffusion on DWI and ADC map(10). The reduced diffusion resolved on 6-30 day follow-up MRI in all children. Conclusion Reversible splenium lesion syndrome has no clinical symptoms and signs. MRI is the best imaging method for diagnosis with reversible changes in signal intensities to avoid inappropriate treatment.
出处 《影像诊断与介入放射学》 2015年第3期238-241,共4页 Diagnostic Imaging & Interventional Radiology
基金 武汉市科技创新平台-儿童神经疾病临床医学研究中心资助项目(武科计2014-160号)
关键词 儿童 可逆性胼胝体压部病变综合征 磁共振成像 Children Reversible splenium lesion syndrome Magnetic resonance imaging
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参考文献9

  • 1Garcia-Monco JC, Cortina IE, Ferreira E, et al. Reversible splenial lesion syndrome (RESLES): What's in a name? J Neuroimaging, 2011,21 : e1-e14.
  • 2Kim SS, Chang KH, Kim ST, et al. Focal lesion in the splenium of the corpus callosum in epileptic patients: antiepileptic drug toxicity? Am J Neuroradiol, 1999,20 : 125-129.
  • 3Kashiwagi M, Tanabe T, Shimakawa S, et al. Clinico-radiological spectrum of reversible splenial lesions in children. Brain Dev, 2014,36 : 330-336.
  • 4黄招君,周美鸿,王博,李辉华,吴裕臣,洪道俊.可逆性胼胝体压部病变综合征3例患者临床特点分析[J].中国神经免疫学和神经病学杂志,2014,21(1):16-19. 被引量:13
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