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糖尿病足发病机制的研究进展 被引量:16

Update in the pathogenesis of diabetic foot
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摘要 糖尿病足是糖尿病的严重并发症,发病机理较为复杂,可能与遗传、神经病变、血管病变、外部压力和感染等相关。在糖尿病足的发生和发展过程中,遗传因素、神经病变和血管病变相互作用。导致体内代谢失调、神经功能紊乱、血液供应和循环障碍。当足部压力异常改变时,引起感染几率增加,进而发生下肢溃疡、坏疽等。 Diabetic foot is a serious complication of diabetes. The pathogenesis of diabetic foot is compli-cated, which may be related to the genetic factors, neuropathy, vasculopathy, pressure and infection. The interaction of genetic factors, neuropathy and vasculopathy results to the metabolic disorder, nerve dysfunc-tion and blood circulatory disturbance. The change of pressure on foot increases the risk of infections, ulcers and gangrene in lower limb.
机构地区 山东大学医学院
出处 《中国麻风皮肤病杂志》 2015年第7期405-407,共3页 China Journal of Leprosy and Skin Diseases
关键词 糖尿病足 发病机理 遗传 神经病变 血管病变 diabetic foot pathogenesis genetics neuropathy vasculopathy
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