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糖尿病下肢血管病变应用辛伐他汀联合舒洛地特治疗的疗效分析 被引量:4

Efficacy of Diabetic Lower Extremity Vascular Lesions with Simvastatin Treatment Sulodexide
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摘要 目的分析糖尿病下肢血管病变应用辛伐他汀联合舒洛地特治疗的效果。方法回顾性分析2013年11月—2014年11月该院收治的43例糖尿病下肢血管病变患者的临床资料,均予辛伐他汀联合舒洛地特治疗,对比患者治疗前后的行走距离、疼痛评分、下肢动脉血流及实验室检查结果。结果治疗后患者无痛和最大行走距离均多于治疗前,VAS评分少于治疗前,下肢动脉的血流速度、阻力指数和搏动指数均优于治疗前,且TC、TG、LDL水平均低于治疗前,差异有统计学意义(P<0.05)。结论糖尿病下肢血管病变应用辛伐他汀联合舒洛地特治疗的效果显著,能够在增加患者行走距离的同时减轻其疼痛感,且可改善患者下肢动脉血流情况与实验室检查情况具备临床实际应用价值。 Objective To analyze the diabetic lower extremity vascular lesions with simvastatin sulodexide therapy.Methods A retrospective analysis in November 2013- November 2014 in our hospital were analyzed the clinical data of 43 patients with diabetic lower extremity vascular lesions,participation in joint ShuLuo simvastatin treatment,compared before and after treatment in patients with walking distance,pain score,lower limb artery blood flow and laboratory test results.Results After treatment in patients with painless and maximum walking distance is more than before the treatment,VAS score less than before the treatment,lower limb artery blood flow velocity,resistance index and pulsation index are better than the before treatment,and the level of TC,TG,LDL was lower than before the treatment,difference have statistical significance(P〈0.05).Conclusion The diabetic lower extremity vascular lesions application simvastatin combined ShuLuo treatment effect is remarkable,walking distance to increase patients and reduce the pain,and can improve patients with lower limb artery blood flow conditions and laboratory examination results.
作者 王永翠
出处 《糖尿病新世界》 2015年第11期34-35,共2页 Diabetes New World Magazine
关键词 辛伐他汀 舒洛地特 糖尿病下肢血管病变 Simvastatin Sulodexide Diabetic lower extremity vascular disease
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  • 1刘芳,曾辉,沈娟,赵俊功,赵珺,包玉倩,贾伟平.门诊2型糖尿病足高危患者的踝肱指数与糖尿病足的相关性研究[J].中华糖尿病杂志,2010,2(1). 被引量:13
  • 2李静宜,李强,王薇,孙予倩,梁玮,张巾超.前列地尔脂微球载体注射液对糖尿病下肢动脉血管病变的影响[J].中国实用内科杂志,2007,27(8):597-599. 被引量:38
  • 3王玉珍,许樟荣.糖尿病足病的检查与诊断分级[J].中国实用内科杂志,2007,27(7):489-492. 被引量:52
  • 4Heng Guan,Yong-jun Li,Zhang-rong XU,Guang-wei Li,Xiao-hui Guo,Zhi-min Liu,Da-jin Zou,Hui-li Xing,Wei Liu,Zheng-yan Sheng,Hao-ming Tian,Da-long Zhu,De-min YU,Wei-te Zhuang,Lu-lu Chen,Jian-ping Weng.PREVALENCE AND RISK FACTORS OF PERIPHERAL ARTERIAL DISEASE IN DIABETIC PATIENTS OVER 50 YEARS OLD IN CHINA[J].Chinese Medical Sciences Journal,2007,22(2):83-88. 被引量:41
  • 5American Diabetes Association. Peripheral arterial disease in people with diabetes [J] . Diabetes Care, 2003, 26 (12): 3333-3341.
  • 6Wood AJJ, Hiatt WR. Medical treatment of peripheral arterial disease and claudication[J]. N Engl J Med, 2001, 344 (21): 1608-1621.
  • 7Jude EB, Eleftheriadou I, Tentolouris N. Peripheral arterial disease in diabetes-a review[J]. Diabet Med, 2010, 27 (1): 4-14.
  • 8Antithrombotic Trialists' Collaboration. Collaborative meta- analysis of randomised trials of antiplatelet therapy for prevention of death, myocardial infarction, and stroke in high risk patients [J]. Br Med J, 2002, 324 (7329): 71-86.
  • 9Belch J, MacCuish A, Campbell I, et al. The prevention of progression of arterial disease and diabetes (POPADAD) xial: factorial randomised placebo controlled trial of aspirin md antioxidants in patients with diabetes and asymptomatic )eripheral arterial disease [J]. Br Meal J, 2008, 337: a1840.
  • 10Mason P J, Jacobs AK, Freedman JE. Aspirin resistance and atherothrombotic disease [J]. J Am Coil Cardiol, 2005, 46 (6) : 986-993.

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